{"id":"W1869202468","doi":"10.1039/c5ob01002k","title":"Synthesis and conformational studies of chiral macrocyclic [1.1.1]metacyclophanes containing benzofuran rings","year":2015,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Engineering and Physical Sciences Research Council","keywords":"Chemistry; Conformational isomerism; Calixarene; Methylene; Hydrogen bond; Medicinal chemistry; Ring (chemistry); Intramolecular force; Benzofuran; Reagent; Cyclophane; Photochemistry; Stereochemistry; Crystallography; Crystal structure; Organic chemistry; Molecule","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006268467,0.0001511708,0.0001783028,0.00007983918,0.0001044094,0.0001197488,0.0001852757,0.00009409285,0.0009159191],"category_scores_gemma":[0.0001233994,0.0000753777,0.0001005482,0.0001115441,0.00007656463,0.0001137152,0.00008744219,0.0002363658,0.0001397751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000179314,"about_ca_system_score_gemma":0.0001067719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006651033,"about_ca_topic_score_gemma":0.001282563,"domain_scores_codex":[0.9999717,0.000002717886,0.000001729378,0.000006426676,0.00000717889,0.00001013147],"domain_scores_gemma":[0.9999609,0.000005519751,0.00001217483,0.000003213817,0.000005474315,0.0000127024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001674794,0.00004401469,0.0003313216,0.0001912688,0.00001024983,0.0002091058,0.00006332484,0.003185475,0.9895962,0.0008930758,0.0001253703,0.005183123],"study_design_scores_gemma":[0.00007367373,0.001531111,0.005215621,0.00002764423,0.00002574362,0.0002832743,0.00007852009,0.01141241,0.9740667,0.0002443929,0.007009738,0.00003117992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971811,0.0008602858,0.0004118641,0.00002053514,0.000008043423,0.00001058283,0.0001326753,0.000008271284,0.001366705],"genre_scores_gemma":[0.9973541,0.0008371071,0.001239177,0.00001113468,0.000003383004,0.000007986616,0.0001556696,0.000004863003,0.0003865203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009159191,"threshold_uncertainty_score":0.003064036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0159165999321167,"score_gpt":0.25734673238267,"score_spread":0.2414301324505533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}