{"id":"W1870122945","doi":"10.1038/leu.2015.264","title":"Clonal dynamics in a single AML case tracked for 9 years reveals the complexity of leukemia progression","year":2015,"lang":"en","type":"article","venue":"Leukemia","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"","keywords":"Leukemia; Dynamics (music); Somatic evolution in cancer; Hematology; Myeloid leukemia; Oncology; Medicine; Biology; Cancer research; Internal medicine; Cancer; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002773923,0.0001014263,0.0002670837,0.001371655,0.0004581965,0.0005422144,0.000245921,0.0004605031,0.001566114],"category_scores_gemma":[0.001277466,0.0001156561,0.0001807316,0.0006723631,0.0001695001,0.0003643165,0.0004376184,0.0004129061,0.000358512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003311406,"about_ca_system_score_gemma":0.0002245441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004143657,"about_ca_topic_score_gemma":0.00489064,"domain_scores_codex":[0.9998484,0.00001508115,0.000011742,0.0000421822,0.00004362455,0.00003889885],"domain_scores_gemma":[0.999494,0.0001503341,0.00009327685,0.00004978719,0.0001114934,0.000101144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"case_report","study_design_scores_codex":[0.0005615794,0.0001107799,0.8497885,0.0000452788,0.0000579465,0.0173828,0.001083918,0.002139716,0.05349359,0.0007696027,0.001968243,0.07259793],"study_design_scores_gemma":[0.00001498306,0.0003008182,0.938836,0.00002964742,0.0001462617,0.02945904,0.0008599543,0.01009628,0.008236974,0.001211959,0.01076882,0.00003915703],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950063,0.0005741285,0.001489772,0.0002374519,0.00001506386,0.00001880587,0.0004674585,0.00005217038,0.002138681],"genre_scores_gemma":[0.9981882,0.0001791699,0.00069643,0.00003916005,0.00002455167,0.000006010774,0.0003807355,0.000009052839,0.0004767548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004143657,"threshold_uncertainty_score":0.00823909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09765468801876845,"score_gpt":0.3593394590796658,"score_spread":0.2616847710608974,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}