{"id":"W1872204365","doi":"10.4049/jimmunol.1400840","title":"Stimulation of the RIG-I/MAVS Pathway by Polyinosinic:Polycytidylic Acid Upregulates IFN-β in Airway Epithelial Cells with Minimal Costimulation of IL-8","year":2015,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Children's Hospital; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Stimulation; Chemokine; Immunology; Inflammation; RIG-I; Cytokine; Interferon; Medicine; Immune system; Chemistry; Innate immune system; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007914664,0.0001813488,0.0004365698,0.0001912802,0.00008495014,0.000005525215,0.000396836,0.0002488669,0.0001851878],"category_scores_gemma":[0.0001434039,0.0001008667,0.0001263593,0.0002454128,0.0004920718,0.000212556,0.00007463562,0.0005553341,0.00003373803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009667623,"about_ca_system_score_gemma":0.0001932451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001897406,"about_ca_topic_score_gemma":0.0000226282,"domain_scores_codex":[0.9978071,0.0008456127,0.0009014845,0.0001109883,0.0001027572,0.000232023],"domain_scores_gemma":[0.9976918,0.0003353881,0.00128165,0.0003066802,0.0003688568,0.00001563757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00581221,0.0002269383,0.001141227,0.000006625614,0.0002093081,6.206777e-7,0.001548812,0.001587856,0.9863713,0.00006107692,0.001385349,0.001648642],"study_design_scores_gemma":[0.003877608,0.002037289,0.01465718,0.00008739036,0.00009163137,0.000205547,0.001113019,0.0001014726,0.9740702,0.00007988307,0.003571753,0.0001070611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993093,0.003274578,0.0003872434,0.0003835917,0.002380736,0.0002205091,0.00001482114,0.000007554287,0.0002379583],"genre_scores_gemma":[0.9987,0.0001052207,0.00003523975,0.00005518901,0.00002973654,0.000001909758,0.00001443274,0.00001610755,0.00104216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01351595,"threshold_uncertainty_score":0.4113224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01128396974464883,"score_gpt":0.2185068080507723,"score_spread":0.2072228383061235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}