{"id":"W1872204365","doi":"10.4049/jimmunol.1400840","title":"Stimulation of the RIG-I/MAVS Pathway by Polyinosinic:Polycytidylic Acid Upregulates IFN-β in Airway Epithelial Cells with Minimal Costimulation of IL-8","year":2015,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Children's Hospital; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Stimulation; Chemokine; Immunology; Inflammation; RIG-I; Cytokine; Interferon; Medicine; Immune system; Chemistry; Innate immune system; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002124893,0.0004311368,0.0003379781,0.0001779766,0.0001386448,0.0004259033,0.0001852173,0.0003481217,0.000993484],"category_scores_gemma":[0.0001166509,0.0001710108,0.000437016,0.0001364034,0.0002552319,0.0002379581,0.0002657342,0.0009526309,0.0005601689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002569606,"about_ca_system_score_gemma":0.0002168893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000411863,"about_ca_topic_score_gemma":0.0005285144,"domain_scores_codex":[0.9996891,0.00006004323,0.00004575539,0.00004870598,0.00007576839,0.00008060997],"domain_scores_gemma":[0.999895,0.00002216582,0.0000261683,0.00002221868,0.00001244163,0.00002202149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005755787,0.00002192885,0.00003721518,0.00002072827,0.000001697617,0.00001237847,0.000008369642,0.00003625442,0.999479,0.00002179508,0.000009954724,0.0002932299],"study_design_scores_gemma":[0.00001975182,0.0004770076,0.001994724,0.000008654449,0.00001218713,0.00006500891,0.00002320249,0.0007838947,0.9955736,0.00001598925,0.001022032,0.000003985485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926972,0.001906881,0.002969338,0.00011678,0.00006098263,0.00007496042,0.0003538266,0.00007277203,0.001747304],"genre_scores_gemma":[0.9936635,0.000850514,0.003351685,0.00006861486,0.00002180621,0.0001013405,0.0004453534,0.00001453078,0.001482598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000993484,"threshold_uncertainty_score":0.003323555,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01128396974464883,"score_gpt":0.2185068080507723,"score_spread":0.2072228383061235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}