{"id":"W1874488229","doi":"10.1016/j.jpsychires.2015.06.015","title":"Antidepressant dose and treatment response in bipolar depression: Reanalysis of the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) data","year":2015,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Eisai; GlaxoSmithKline; Pfizer","keywords":"Hypomania; Mood stabilizer; Bipolar disorder; Antidepressant; Mania; Placebo; Depression (economics); Adjunctive treatment; Randomized controlled trial; Mood; Medicine; Internal medicine; Bipolar II disorder; Psychiatry; Anxiety","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01347236,0.0006047699,0.002013697,0.003368046,0.0003720792,0.0008340894,0.001408019,0.0006032073,0.001476959],"category_scores_gemma":[0.04225594,0.0006055938,0.005964152,0.005064283,0.0003293222,0.0007398556,0.001509464,0.001046883,0.0002147093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001161633,"about_ca_system_score_gemma":0.002935257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03044029,"about_ca_topic_score_gemma":0.05158414,"domain_scores_codex":[0.9772974,0.01331166,0.003441548,0.001932121,0.003520787,0.0004964905],"domain_scores_gemma":[0.9606501,0.0215607,0.008948954,0.004975056,0.003381976,0.0004832483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.006628682,0.0002227295,0.9008353,0.004169817,0.03868527,0.0001489734,0.0007882449,0.001652149,0.000919106,0.0002293253,0.008317653,0.03740276],"study_design_scores_gemma":[0.0006378603,0.0005622973,0.9836764,0.0003787895,0.009302638,0.0001186792,0.000293788,0.001702138,0.0003559179,0.0001123433,0.002820019,0.00003917871],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9097705,0.007769839,0.004784668,0.0006132952,0.0001448903,0.001333858,0.07412779,0.0002703363,0.001184896],"genre_scores_gemma":[0.9625967,0.001166001,0.006228525,0.0003067595,0.00005128714,0.001558128,0.02735836,0.0001010859,0.0006330871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03044029,"threshold_uncertainty_score":0.07124954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1112873838975807,"score_gpt":0.4289354523141606,"score_spread":0.31764806841658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}