{"id":"W1876898604","doi":"10.1183/13993003/erj.44.suppl_58.1929","title":"Analysis of overall survival (OS) in two large open-label phase III studies (LUX-Lung 3 [LL3] and LUX-Lung 6 [LL6]) comparing afatinib with chemotherapy (CT) in patients (pts) with advanced non-small cell lung cancer (NSCLC) harboring common (Del19/L858R) epidermal growth factor receptor mutations (EGFR mut)","year":2014,"lang":"en","type":"article","venue":"European Respiratory Journal","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Afatinib; Internal medicine; Pemetrexed; Oncology; Gemcitabine; Lung cancer; Erlotinib; Progression-free survival; Cisplatin; Gastroenterology; Chemotherapy; Epidermal growth factor receptor; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01101036,0.001280121,0.002407443,0.0008335817,0.0003284455,0.001087313,0.0008173033,0.001209575,0.002227529],"category_scores_gemma":[0.005639825,0.0005030608,0.005499468,0.00100545,0.00102439,0.001001613,0.0008760685,0.001869498,0.000266889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001200749,"about_ca_system_score_gemma":0.0009628669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005581152,"about_ca_topic_score_gemma":0.001492238,"domain_scores_codex":[0.9952419,0.003209798,0.0003677443,0.0005679368,0.0003864056,0.0002262084],"domain_scores_gemma":[0.9942583,0.002327539,0.001779012,0.0005682538,0.0003545645,0.0007123619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.859935,0.004928223,0.05065014,0.001456543,0.03605519,0.0001273979,0.0001842774,0.002771659,0.007461356,0.00009254552,0.001024013,0.03531366],"study_design_scores_gemma":[0.2941748,0.3972896,0.2443093,0.0002153638,0.05091573,0.0006371052,0.0002593192,0.00392822,0.004564383,0.0004863028,0.003098071,0.0001218012],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907213,0.0059573,0.0009699216,0.0001276777,0.00005182299,0.0005061916,0.001138497,0.00003333608,0.0004939309],"genre_scores_gemma":[0.9950979,0.001112652,0.0006799157,0.0002220231,0.00009010713,0.0004891746,0.001982411,0.00001744665,0.00030831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01101036,"threshold_uncertainty_score":0.05822909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03315278903181521,"score_gpt":0.3644243378249853,"score_spread":0.3312715487931701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}