{"id":"W1877580702","doi":"10.1093/molehr/gav058","title":"Induction of interferon-λ contributes to TLR3 and RIG-I activation-mediated inhibition of herpes simplex virus type 2 replication in human cervical epithelial cells","year":2015,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Drug Abuse; Fundamental Research Funds for the Central Universities; State Key Laboratory of Virology; Chinese Academy of Sciences; China Postdoctoral Science Foundation; Hubei Key Laboratory of Wudang Local Chinese Medicine Research; Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China; McGill University","keywords":"IRF3; Biology; TLR3; Interferon; Herpes simplex virus; Western blot; IRF7; Virology; RIG-I; Viral replication; Transfection; Cell culture; Molecular biology; Innate immune system; Virus; Receptor; Toll-like receptor; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002744071,0.0003100194,0.0003038586,0.0002057189,0.0001876496,0.0003749178,0.0001624927,0.0003329939,0.00299192],"category_scores_gemma":[0.0002233603,0.0001546828,0.000762344,0.000135454,0.0002087352,0.0002012544,0.0003341562,0.0004790796,0.0007598939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002661181,"about_ca_system_score_gemma":0.000293181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003885881,"about_ca_topic_score_gemma":0.0003600406,"domain_scores_codex":[0.9997538,0.00004603884,0.00002429063,0.00004836678,0.00005799787,0.00006952049],"domain_scores_gemma":[0.9998854,0.00002434592,0.00002776607,0.0000252389,0.00001937039,0.00001780608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002688773,0.00004679664,0.0006355563,0.0001231633,0.000008483717,0.00007530497,0.00003731999,0.00004154589,0.9968358,0.00006507972,0.00005218999,0.001809913],"study_design_scores_gemma":[0.00003424849,0.0005367367,0.01285348,0.00002428748,0.00003323982,0.0004755346,0.00009323031,0.0008012779,0.9821013,0.00008246862,0.002957612,0.000006547468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870026,0.004851293,0.004106541,0.0002158441,0.00008170809,0.0001085295,0.0005780171,0.00007466616,0.002980897],"genre_scores_gemma":[0.9929752,0.001462284,0.002072276,0.0001394045,0.00002152661,0.0001070556,0.0006977786,0.00001091724,0.002513567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00299192,"threshold_uncertainty_score":0.01000893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03222705722359435,"score_gpt":0.3171392838671978,"score_spread":0.2849122266436034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}