{"id":"W1878836154","doi":"10.14740/jem.v5i5.302","title":"Harnessing Structural Data of Insulin and Insulin Receptor for Therapeutic Designs","year":2015,"lang":"en","type":"article","venue":"Journal of Endocrinology and Metabolism","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Insulin; Insulin receptor; Medicine; Insulin delivery; Receptor; Diabetes mellitus; Internal medicine; Endocrinology; Insulin resistance; Type 1 diabetes","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003828202,0.0001380968,0.0003944175,0.00007991362,0.00004931422,0.00001588835,0.0002542528,0.0001128975,0.000007766421],"category_scores_gemma":[0.0002425683,0.0001066527,0.00005337819,0.00004847281,0.0001914953,0.00002633088,0.0001291144,0.0001324306,2.616985e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003593569,"about_ca_system_score_gemma":0.0001660326,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006149698,"about_ca_topic_score_gemma":0.000004060106,"domain_scores_codex":[0.9989738,0.0001186097,0.0003796997,0.0002057579,0.00009696481,0.0002251075],"domain_scores_gemma":[0.9989979,0.00003621085,0.0003404698,0.0002491272,0.0002538468,0.0001224233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001011679,0.00005892416,0.001405079,0.00006415479,0.0004575201,0.00000336676,0.0003431099,0.00001139253,0.1516611,0.001724842,0.002575462,0.8406834],"study_design_scores_gemma":[0.005077119,0.0003853785,0.005767491,0.00002212337,0.0003151067,0.000195873,0.0003248428,0.00005473447,0.1091182,0.002842932,0.8756817,0.0002144531],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5365613,0.4619421,0.0007580285,0.00007437719,0.0005294053,0.00007171852,0.00004340702,0.000001541804,0.0000181309],"genre_scores_gemma":[0.8915755,0.1009334,0.006226772,0.0003198042,0.0008439817,0.000004385335,0.00003457478,0.00001780957,0.00004377233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8731062,"threshold_uncertainty_score":0.4349169,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07505874821573669,"score_gpt":0.3258094904688212,"score_spread":0.2507507422530846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}