{"id":"W1880712737","doi":"10.1038/ng.3426","title":"Small island, big genetic discoveries","year":2015,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Biology; Imputation (statistics); Genetics; Genetic variation; Phenotype; Genotype; Evolutionary biology; Genome-wide association study; Human genetic variation; Computational biology; Genome; Gene; Human genome; Single-nucleotide polymorphism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008626971,0.0006920914,0.001231478,0.002468503,0.001686182,0.004439846,0.001544393,0.001904953,0.01142008],"category_scores_gemma":[0.01588396,0.0007629549,0.000670959,0.002240621,0.003309999,0.005050796,0.004361361,0.006058294,0.002180747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001686355,"about_ca_system_score_gemma":0.003248873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006112617,"about_ca_topic_score_gemma":0.01417358,"domain_scores_codex":[0.9977816,0.0006670937,0.0001272559,0.000526658,0.0006698433,0.0002275316],"domain_scores_gemma":[0.9789641,0.008460931,0.001010242,0.003593931,0.003019535,0.004951189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001035078,0.0003130428,0.1219407,0.001701141,0.00230621,0.00378325,0.002859164,0.0009233354,0.01418366,0.08761524,0.279515,0.4838242],"study_design_scores_gemma":[0.0002597987,0.0002786423,0.2390845,0.0009251043,0.001164356,0.002514256,0.003783065,0.001466558,0.001998376,0.2707956,0.4775589,0.0001707555],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.2394772,0.1045345,0.08902287,0.3453621,0.03173603,0.0004855859,0.01239513,0.004349987,0.1726366],"genre_scores_gemma":[0.6965125,0.04758096,0.06939521,0.09817526,0.02466641,0.0004360729,0.005529938,0.001305937,0.05639772],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01142008,"threshold_uncertainty_score":0.04562432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02028909355062966,"score_gpt":0.2619249123927515,"score_spread":0.2416358188421218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}