{"id":"W1880868311","doi":"10.1080/15548627.2015.1009794","title":"USP8 and PARK2/parkin-mediated mitophagy","year":2015,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Mitophagy; Parkin; Ubiquitin; Deubiquitinating enzyme; Biology; Ubiquitin ligase; PINK1; Cell biology; Mitochondrion; Autophagy; Ubiquitin-Protein Ligases; Ubiquitin-conjugating enzyme; Biochemistry; Parkinson's disease; Gene; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001997566,0.0002270885,0.0003764574,0.0001146193,0.00006317769,0.00002925844,0.0001022866,0.0001508719,0.0003356187],"category_scores_gemma":[0.0001710261,0.0001937831,0.00008648006,0.0002205887,0.0001454189,0.0001232541,0.00005871122,0.0001820825,0.0004727056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005580662,"about_ca_system_score_gemma":0.0002232149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004755614,"about_ca_topic_score_gemma":0.000002967396,"domain_scores_codex":[0.9985909,0.00005600957,0.000274395,0.0003644865,0.0003404001,0.0003737691],"domain_scores_gemma":[0.9986634,0.0000863836,0.00007509418,0.0004070396,0.000112063,0.0006560726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.008369806,0.005843159,0.1789293,0.0009582745,0.004765214,0.01543826,0.01204072,0.00004383013,0.157745,0.02619217,0.3160455,0.2736287],"study_design_scores_gemma":[0.02073622,0.001955851,0.4204239,0.0001787592,0.0005109612,0.001031806,0.0005170983,0.00217958,0.1091228,0.006722771,0.4354994,0.001120934],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9770139,0.00903984,0.00007067525,0.000738224,0.0004276818,0.0003258907,0.00001365716,0.0002751613,0.01209501],"genre_scores_gemma":[0.9926186,0.0002234287,0.0004775969,0.002855666,0.0003774406,0.00003375201,0.00005811455,0.00004276542,0.003312617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2725078,"threshold_uncertainty_score":0.7902246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03420614248880946,"score_gpt":0.2886155742192049,"score_spread":0.2544094317303954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}