{"id":"W1882824745","doi":"10.18632/oncotarget.1198","title":"Identification of novel small molecule inhibitors of centrosome clustering in cancer cells","year":2013,"lang":"en","type":"article","venue":"Oncotarget","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"BC Cancer Agency; Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance","keywords":"Centrosome; Clonogenic assay; Mitosis; Cancer research; Cancer cell; Biology; Breast cancer; Cancer; Cell biology; Cell culture; Cell cycle; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001424021,0.0005615679,0.0006812474,0.0005617319,0.0002240031,0.0003702936,0.0003729096,0.0003229146,0.001581477],"category_scores_gemma":[0.0001072064,0.0002284169,0.0003739967,0.0003495594,0.0001226441,0.0001635056,0.0002539544,0.0005864626,0.00071486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003493936,"about_ca_system_score_gemma":0.0003214222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005557866,"about_ca_topic_score_gemma":0.002288631,"domain_scores_codex":[0.9999058,0.000007633307,0.00000896339,0.00001761436,0.00003808146,0.00002196836],"domain_scores_gemma":[0.999926,0.0000134472,0.00001278624,0.000007366211,0.00002104944,0.00001930578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001524433,0.0001932657,0.0003338539,0.0001424901,0.00002844223,0.0001030169,0.00001361141,0.0003617883,0.9833906,0.000222696,0.0004485637,0.01460923],"study_design_scores_gemma":[0.000384095,0.002367034,0.005826422,0.00002588862,0.0001374946,0.0007098729,0.00003048495,0.003466059,0.9685991,0.0001059042,0.01832543,0.00002215926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.953261,0.01862842,0.01283567,0.0005684605,0.0001743012,0.0009057229,0.001602528,0.0005799465,0.01144394],"genre_scores_gemma":[0.9622431,0.01261782,0.0113478,0.0003615785,0.00004662835,0.0005240365,0.003459588,0.00007405101,0.009325546],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001581477,"threshold_uncertainty_score":0.005290627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008816535229123512,"score_gpt":0.2359145982686565,"score_spread":0.227098063039533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}