{"id":"W1884135731","doi":"10.1002/ptr.5363","title":"Preclinical Pharmacokinetics and Pharmacodynamics and Content Analysis of Gnetol in Foodstuffs","year":2015,"lang":"en","type":"article","venue":"Phytotherapy Research","topic":"Natural Compound Pharmacology Studies","field":"Agricultural and Biological Sciences","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital; University of Manitoba","funders":"","keywords":"Pharmacology; Bioavailability; Viability assay; Chemistry; Histone deacetylase; Pharmacokinetics; Pharmacodynamics; Metabolite; Cyclooxygenase; Aglycone; Urine; Biochemistry; Medicine; In vitro; Enzyme; Glycoside; Histone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000423318,0.0005389762,0.000598123,0.0004791262,0.0001837189,0.0003692681,0.0004083206,0.0005671924,0.002561692],"category_scores_gemma":[0.000483328,0.0002868319,0.0004246354,0.0003389004,0.0003081626,0.0003757229,0.0001754882,0.001223875,0.0004858678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004609982,"about_ca_system_score_gemma":0.0004647583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008096205,"about_ca_topic_score_gemma":0.001266136,"domain_scores_codex":[0.9998695,0.00003296993,0.000007524508,0.00002723665,0.00003377719,0.00002905773],"domain_scores_gemma":[0.9997249,0.00005401346,0.00007801383,0.0000323204,0.00005425435,0.00005647303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02074156,0.009083588,0.003260076,0.0003598391,0.0001584871,0.0002917578,0.0001548309,0.002612913,0.9087034,0.0003972783,0.0009974025,0.0532388],"study_design_scores_gemma":[0.002345645,0.2502432,0.0264922,0.00007814489,0.0004612889,0.0008728907,0.0002394565,0.006341361,0.6963854,0.0004508251,0.01601221,0.00007748938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906425,0.001137858,0.004067343,0.0001498837,0.00004887479,0.0004769967,0.001127577,0.000160158,0.00218879],"genre_scores_gemma":[0.9847498,0.002189738,0.003784789,0.0002304829,0.00003224302,0.0006182806,0.002190702,0.00005093917,0.006153056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002561692,"threshold_uncertainty_score":0.008569717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4775091999149522,"score_gpt":0.4803426474649741,"score_spread":0.00283344755002185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}