{"id":"W1884480099","doi":"10.1562/0031-8655(2000)0720554ueeoar2.0.co2","title":"UV-enhanced Expression of a Reporter Gene is Induced at Lower UV Fluences in Transcription-coupled Repair Deficient Compared to Normal Human Fibroblasts, and is Absent in SV40-transformed Counterparts¶","year":2000,"lang":"en","type":"article","venue":"Photochemistry and Photobiology","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Cancer Institute","keywords":"Xeroderma pigmentosum; Reporter gene; Biology; Nucleotide excision repair; HeLa; Molecular biology; Promoter; Gene; Cockayne syndrome; Transcription (linguistics); Pyrimidine dimer; Cell culture; Gene expression; DNA repair; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002801792,0.000240641,0.000596097,0.0001244372,0.00008504645,0.00001205167,0.00009131483,0.0002465318,0.002706579],"category_scores_gemma":[0.00001449087,0.0002103957,0.00009629859,0.0002072571,0.0001883371,0.00005540811,0.00003907632,0.0002532073,0.000004961605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009393534,"about_ca_system_score_gemma":0.00007895361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001054145,"about_ca_topic_score_gemma":0.000579494,"domain_scores_codex":[0.9980295,0.00003713301,0.0007042366,0.0005989151,0.0002026316,0.0004276306],"domain_scores_gemma":[0.9992939,0.00004614892,0.00008340176,0.0003082623,0.00006641306,0.0002018566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004317043,0.0002820267,0.01311081,0.0002768368,0.00002447282,0.00006127848,0.003773421,0.000004316971,0.9777812,2.367213e-7,0.000209585,0.0001588101],"study_design_scores_gemma":[0.002762951,0.0004411265,0.02405135,0.0003708492,0.00001744278,0.0001143157,0.000195821,0.0003098071,0.9703981,0.00001101151,0.001119802,0.0002074395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977344,0.0002630067,0.00000220581,0.00009600955,0.00002474912,0.000965487,0.00008154783,0.00001941589,0.0008131341],"genre_scores_gemma":[0.9985434,0.0002184763,0.00006008416,0.0004269797,0.00002597336,0.0002218396,0.00006929083,0.00001413111,0.0004198287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01094055,"threshold_uncertainty_score":0.9982051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02308226150499636,"score_gpt":0.3044052883991891,"score_spread":0.2813230268941927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}