{"id":"W1886211687","doi":"10.1002/cpt.284","title":"Emerging monoclonal antibodies as targeted innovative therapeutic approaches to asthma","year":2015,"lang":"en","type":"review","venue":"Clinical Pharmacology & Therapeutics","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Omalizumab; Asthma; Immunology; Medicine; Monoclonal antibody; Immunoglobulin E; Cytokine; Mepolizumab; Antibody; Allergy; Eosinophil","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007335928,0.0009597464,0.001385312,0.002530716,0.0002680383,0.001021595,0.00105324,0.001235034,0.004233762],"category_scores_gemma":[0.0006118279,0.0003640307,0.000698431,0.001736762,0.0004996341,0.00127852,0.0008623247,0.002765151,0.002503304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006223705,"about_ca_system_score_gemma":0.0006906721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000730044,"about_ca_topic_score_gemma":0.001576863,"domain_scores_codex":[0.9997514,0.00004493015,0.00002677514,0.00003540255,0.0001035532,0.00003785641],"domain_scores_gemma":[0.9998158,0.00007624075,0.00002861009,0.000007015403,0.00005076918,0.00002164221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001228041,0.000199148,0.0001524568,0.01302462,0.0001354238,0.0002730337,0.00007282909,0.0004666148,0.004162013,0.007733602,0.02642124,0.9472364],"study_design_scores_gemma":[0.00004678676,0.0001324521,0.0003937726,0.001635061,0.00008710329,0.0008656023,0.00002736248,0.00009711654,0.0007402487,0.001959392,0.9940009,0.00001429652],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001997288,0.9980518,0.0001760266,0.0001940319,0.0002226613,0.00001194646,0.00001853542,0.00001009979,0.001115212],"genre_scores_gemma":[0.001064207,0.9972739,0.0002860845,0.0002962216,0.000156661,0.00001512641,0.00004278574,0.000001986793,0.0008631223],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004233762,"threshold_uncertainty_score":0.01416332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4073594702037661,"score_gpt":0.5071271919195822,"score_spread":0.0997677217158161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}