{"id":"W1886612565","doi":"10.1038/emboj.2011.234","title":"Nedd4‐1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function","year":2011,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Health Canada; Canada Research Chairs","keywords":"Biology; Endocytosis; Function (biology); Cell biology; NEDD4; Receptor; Genetics; Ubiquitin; Ubiquitin ligase; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004182025,0.0004003364,0.0003357044,0.0002711663,0.0004719804,0.0008925552,0.0005714652,0.0004262859,0.002141517],"category_scores_gemma":[0.0003712364,0.0004382851,0.0003997888,0.0001619063,0.0005149019,0.0006445672,0.0006056755,0.0007766652,0.0009521092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001499993,"about_ca_system_score_gemma":0.0003846069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009495482,"about_ca_topic_score_gemma":0.00173767,"domain_scores_codex":[0.9995906,0.00004866005,0.00003250984,0.0001154172,0.0001134099,0.00009933185],"domain_scores_gemma":[0.9998707,0.00001245092,0.0000384995,0.0000168513,0.0000220353,0.00003941317],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003146879,0.0000163698,0.0004641506,0.00007015419,0.00001397315,0.0001378914,0.00002282822,0.0001537242,0.9951714,0.000764165,0.0002878607,0.002582769],"study_design_scores_gemma":[0.00002461814,0.00005023661,0.003622197,0.00000382621,0.000009605488,0.0003439818,0.00003146078,0.00140131,0.9887938,0.0001475259,0.00555948,0.00001210187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809276,0.006524087,0.006832687,0.0004884929,0.0001866415,0.00002971916,0.0005056186,0.0001689779,0.004336047],"genre_scores_gemma":[0.987985,0.0009723683,0.003510154,0.0001065064,0.00001973502,0.00001791484,0.0008503387,0.00005847222,0.006479532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002141517,"threshold_uncertainty_score":0.01088327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02395445443054342,"score_gpt":0.2517987802855931,"score_spread":0.2278443258550497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}