{"id":"W1887565043","doi":"10.1593/neo.131870","title":"Tumor-Suppressive Activity of Lunatic Fringe in Prostate through Differential Modulation of Notch Receptor Activation","year":2014,"lang":"en","type":"article","venue":"Neoplasia","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; SickKids Foundation","funders":"National Cancer Institute","keywords":"Notch signaling pathway; HES1; Prostate cancer; Biology; Cancer research; Prostate; Carcinogenesis; Cell biology; Endocrinology; Signal transduction; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008692697,0.0001067354,0.0002909753,0.0001059067,0.00002085447,0.000004946374,0.0000486438,0.00005252958,0.00007827644],"category_scores_gemma":[0.00009596151,0.00008485873,0.00005013624,0.0001997495,0.00006648213,0.0001643688,0.00002981734,0.0001472489,0.000004242169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001034266,"about_ca_system_score_gemma":0.00007714141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002089143,"about_ca_topic_score_gemma":0.00001645531,"domain_scores_codex":[0.9990513,0.00007194014,0.0002140862,0.0001847854,0.0003082847,0.0001695583],"domain_scores_gemma":[0.9994202,0.00008038911,0.0001668639,0.0001812977,0.0001131091,0.00003810324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002032473,0.0005006026,0.07080423,0.0005292756,0.00004738054,0.000002336808,0.002045413,0.00006586759,0.905236,0.0001754852,0.0001233628,0.01843756],"study_design_scores_gemma":[0.002958313,0.0003650771,0.3611179,0.0002848205,0.00002039836,0.000001787884,0.00005342043,0.004078539,0.6307268,0.000255462,0.00007314263,0.00006431381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974398,0.00001328183,0.0005002793,0.0003013517,0.00008060075,0.0005805714,0.00001236468,0.00001437033,0.001057356],"genre_scores_gemma":[0.9992405,0.00002266284,0.0003401291,0.000009177158,0.00004456305,0.00004053276,0.00004979242,0.00001434211,0.0002383078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2903137,"threshold_uncertainty_score":0.3460439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0175157365816881,"score_gpt":0.294652094856362,"score_spread":0.2771363582746739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}