{"id":"W1890200017","doi":"10.4049/jimmunol.180.3.1737","title":"Infection with <i>Trypanosoma cruzi</i> Restricts the Repertoire of Parasite-Specific CD8+ T Cells Leading to Immunodominance","year":2008,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Universidade Federal do Rio de Janeiro; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa do Estado de São Paulo; York University","keywords":"Immunodominance; Biology; Epitope; Virology; Trypanosoma cruzi; CD8; Immune system; Antigen; Immunology; Parasite hosting","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001638656,0.0003283807,0.00030813,0.0001390245,0.0001059033,0.0003701056,0.0001848558,0.0002833539,0.0008920031],"category_scores_gemma":[0.0001113511,0.0001664424,0.0001982396,0.00007216985,0.0002794029,0.0001527698,0.0002309857,0.0005052451,0.0003898446],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002087917,"about_ca_system_score_gemma":0.0001592845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002981662,"about_ca_topic_score_gemma":0.0006498732,"domain_scores_codex":[0.9997306,0.00004001647,0.00002948115,0.00006793658,0.00005113911,0.00008087205],"domain_scores_gemma":[0.9998098,0.00003578785,0.00006557311,0.00002272552,0.00001383794,0.00005232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000376987,0.000008134642,0.000197027,0.00001125355,0.000001253565,0.00001574663,0.000005401633,0.000006852846,0.9994487,0.00002507669,0.000008551187,0.0002342163],"study_design_scores_gemma":[0.00002675812,0.0007440111,0.01130655,0.00001212057,0.00002486649,0.0006977829,0.00005481044,0.0005970005,0.9847806,0.00005520241,0.001692549,0.00000777924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967542,0.0008021038,0.001243055,0.00004738595,0.00001206118,0.00001580403,0.00007959292,0.00005308827,0.0009926186],"genre_scores_gemma":[0.9977648,0.0004009448,0.000795036,0.00005471639,0.00001198087,0.00001928865,0.0001691446,0.00001992182,0.00076411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008920031,"threshold_uncertainty_score":0.002984107,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02901998720082129,"score_gpt":0.2774930091408246,"score_spread":0.2484730219400033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}