{"id":"W1890648625","doi":"10.3390/biom5042935","title":"The RNA Splicing Response to DNA Damage","year":2015,"lang":"en","type":"review","venue":"Biomolecules","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":156,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"RNA splicing; Alternative splicing; Splicing factor; DNA damage; Ribonucleoprotein; Biology; Cell biology; DNA repair; RNA; Minigene; Genetics; Exonic splicing enhancer; SR protein; DNA; Gene; Computational biology; Exon","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004065338,0.0007267559,0.0009698046,0.001430396,0.0003438414,0.001056301,0.0006912769,0.001032779,0.004334275],"category_scores_gemma":[0.0004020138,0.0002414772,0.0003548586,0.001313071,0.0006881689,0.00104473,0.0007548224,0.001366912,0.004145108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005989578,"about_ca_system_score_gemma":0.0007708615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004841141,"about_ca_topic_score_gemma":0.0006879289,"domain_scores_codex":[0.9998537,0.00002146326,0.00002026558,0.00003291732,0.00005337579,0.00001819109],"domain_scores_gemma":[0.9998215,0.0000635736,0.00003133068,0.000008729795,0.00004979438,0.00002509128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005566637,0.00003315493,0.0001744012,0.009597525,0.00005318657,0.0003161376,0.0001040154,0.0003904591,0.01024052,0.00856638,0.0222485,0.9482202],"study_design_scores_gemma":[0.000004409885,0.0000405127,0.0004074263,0.0008547711,0.00002612926,0.001050837,0.00003441621,0.0000448176,0.001878676,0.002539678,0.9931073,0.00001112585],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002585008,0.9948804,0.0004482904,0.0003100298,0.0003068561,0.000008188919,0.00003561384,0.00002319996,0.00372884],"genre_scores_gemma":[0.001607551,0.9955119,0.0003053001,0.0001836952,0.0002153768,0.000009999338,0.00006196897,0.00000390891,0.002100202],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004334275,"threshold_uncertainty_score":0.0144996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04400020358332041,"score_gpt":0.3748516824659635,"score_spread":0.330851478882643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}