{"id":"W1890648625","doi":"10.3390/biom5042935","title":"The RNA Splicing Response to DNA Damage","year":2015,"lang":"en","type":"review","venue":"Biomolecules","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":156,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"RNA splicing; Alternative splicing; Splicing factor; DNA damage; Ribonucleoprotein; Biology; Cell biology; DNA repair; RNA; Minigene; Genetics; Exonic splicing enhancer; SR protein; DNA; Gene; Computational biology; Exon","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001449383,0.0003741037,0.0005445124,0.0001239373,0.00024275,0.0002136123,0.0008901439,0.0002901203,0.000004255028],"category_scores_gemma":[0.0007874567,0.0002394184,0.000328086,0.0003028045,0.0001535466,0.000002627877,0.0005598243,0.0001977415,0.0002222819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006958304,"about_ca_system_score_gemma":0.0006202084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003255266,"about_ca_topic_score_gemma":0.0000455638,"domain_scores_codex":[0.9975718,0.0005719893,0.0003797545,0.000549885,0.0003388184,0.0005877058],"domain_scores_gemma":[0.9982488,0.00009556789,0.0001305532,0.001029967,0.0001361852,0.0003589384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000228762,0.00001957897,2.826643e-7,0.0004841649,0.0001359297,0.00004866915,0.00001207386,4.355097e-7,0.120688,0.00006759266,0.02173195,0.8565826],"study_design_scores_gemma":[0.000117949,0.0002601587,0.000001734203,0.0007157415,0.00005220383,0.00002793595,0.00003932928,0.000001781477,0.003231894,0.000006193181,0.9952427,0.0003024308],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002954835,0.99496,0.0001842823,0.0002262742,0.0001546456,0.0006711945,0.00004695911,0.00002004689,0.0007817887],"genre_scores_gemma":[0.0001047565,0.9906562,0.0002063458,0.0001153032,0.0003572273,0.0001243938,0.0001190151,0.00008645091,0.008230333],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9735107,"threshold_uncertainty_score":0.97632,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04400020358332041,"score_gpt":0.3748516824659635,"score_spread":0.330851478882643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}