{"id":"W1891365510","doi":"10.4049/jimmunol.1302287","title":"Antibody-Mediated Immune Suppression of Erythrocyte Alloimmunization Can Occur Independently from Red Cell Clearance or Epitope Masking in a Murine Model","year":2014,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Blood groups and transfusion","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Canadian Blood Services; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Epitope; Isotype; Antibody; Monoclonal antibody; Immunogen; Immunology; Ovalbumin; Immune system; Chemistry; Polyclonal antibodies; Immunogenicity; Molecular biology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007178246,0.0001579271,0.0006077989,0.0002166041,0.00006344531,0.000005743852,0.0003122624,0.0001915023,0.00007897688],"category_scores_gemma":[0.0001424248,0.00009732776,0.0000916742,0.0002532672,0.0001087614,0.0001119081,0.00008599948,0.0006998298,0.000002842359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004237846,"about_ca_system_score_gemma":0.0001206788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006758364,"about_ca_topic_score_gemma":0.0001117523,"domain_scores_codex":[0.9982474,0.0003086001,0.0008432319,0.0001170621,0.0002547945,0.0002289239],"domain_scores_gemma":[0.9985405,0.0002223236,0.0006269134,0.0003662246,0.0002042076,0.00003988114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006957335,0.0003329322,0.003659156,0.00004217381,0.0001136606,0.00002714693,0.001861751,0.001625227,0.9832551,0.00001256501,0.00001102919,0.002101918],"study_design_scores_gemma":[0.0236209,0.002841047,0.4547446,0.001888067,0.0004993152,0.0005314091,0.001165784,0.03138786,0.4820848,0.0006395,0.000295705,0.0003010597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912922,0.00263394,0.00453784,0.0009580423,0.0002425655,0.0001851937,0.000007431279,0.00001004658,0.0001326807],"genre_scores_gemma":[0.9937446,0.005333636,0.0006301885,0.0001075791,0.0000592072,9.622493e-7,0.00004235199,0.00002587743,0.00005559987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5011703,"threshold_uncertainty_score":0.3968911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01023679802573613,"score_gpt":0.2461267386275163,"score_spread":0.2358899406017801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}