{"id":"W1891795013","doi":"10.1016/j.molcel.2015.08.005","title":"Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event","year":2015,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; University of Toronto; Lunenfeld-Tanenbaum Research Institute","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; Howard Hughes Medical Institute; U.S. Public Health Service; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Biology; Helicase; Chromatin; Chaperone (clinical); Histone; Histone H2A; Histone code; Cell biology; Histone H3; Protein subunit; Proteome; Interactome; Histone H1; Histone methyltransferase; Genetics; Biochemistry; Nucleosome; DNA; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003506876,0.0001009666,0.0001395224,0.0000448991,0.00005791678,0.00001281343,0.0002695082,0.00007874947,0.00001599348],"category_scores_gemma":[0.00008955181,0.00006192485,0.0002575855,0.0002429095,0.00005499235,0.000001649843,0.0001124664,0.00005313767,0.000001861212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002035229,"about_ca_system_score_gemma":0.00005628294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004226611,"about_ca_topic_score_gemma":0.00005806002,"domain_scores_codex":[0.9992186,0.00006777512,0.0001943028,0.0001995941,0.0001659127,0.0001538113],"domain_scores_gemma":[0.9991181,0.00002513593,0.0001282895,0.0005267369,0.0001520746,0.00004966918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003867465,0.00008142043,0.0009883996,0.000009755096,0.0002957548,5.558301e-7,0.0001390018,0.006306964,0.9909492,0.00009308374,0.0004059176,0.0006912819],"study_design_scores_gemma":[0.00035251,0.0001252103,0.001218495,0.000002738106,0.0004677894,2.246494e-7,0.00004424546,0.002995341,0.9010201,0.0000929617,0.09358478,0.00009561751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9269679,0.007605536,0.06271114,0.0003234394,0.0002224273,0.0003428731,0.00002815215,0.00000358671,0.001794936],"genre_scores_gemma":[0.997431,0.00005803298,0.0003177911,0.0001395436,0.00003667833,0.0000328513,0.0000709396,0.00001463811,0.001898556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09317886,"threshold_uncertainty_score":0.2525222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01110810071090589,"score_gpt":0.2757122722417103,"score_spread":0.2646041715308044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}