{"id":"W1893872461","doi":"10.1002/eji.201445156","title":"Redirecting soluble antigen for MHC class I cross‐presentation during phagocytosis","year":2014,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation; Natural Sciences and Engineering Research Council of Canada; Tsinghua University","keywords":"Antigen processing; Endosome; MHC class I; Cross-presentation; Antigen presentation; Endocytosis; Biology; Cell biology; MHC class II; Antigen; Endocytic cycle; MHC restriction; Phagocytosis; CD74; Lysosome; Major histocompatibility complex; Transporter associated with antigen processing; Epitope; CD1; Antigen-presenting cell; T cell; Immune system; Immunology; Cell; Biochemistry; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002046352,0.0002338253,0.0004757768,0.0003128981,0.0005346086,0.00005736942,0.0005608913,0.0001279273,0.0002167583],"category_scores_gemma":[0.0007841447,0.000209333,0.0003151839,0.0001369604,0.0002547558,0.0003033078,0.0001018209,0.0005012928,0.0001908263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007235656,"about_ca_system_score_gemma":0.00005915211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001276456,"about_ca_topic_score_gemma":0.000001084671,"domain_scores_codex":[0.996498,0.001756192,0.0009480375,0.0002285789,0.00005155348,0.0005176346],"domain_scores_gemma":[0.9979217,0.0005202895,0.0008753063,0.000322123,0.0003391045,0.00002144686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003508728,0.00009399204,0.001480549,0.00001756684,0.0006379763,0.00001316466,0.0009695051,0.00003940116,0.9701926,0.00008414567,0.000856568,0.02210577],"study_design_scores_gemma":[0.007492401,0.001473638,0.05081006,0.00009622003,0.00005485484,0.001143752,0.0004444025,0.000007425055,0.7675982,0.00004871723,0.1705666,0.0002637653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822982,0.009142329,0.002790243,0.0003511141,0.003716472,0.0001642306,0.000004593875,0.00005552525,0.001477305],"genre_scores_gemma":[0.9940277,0.000611079,0.0004787503,0.0001194803,0.0002353501,0.000003949582,0.0000152236,0.00006359207,0.004444902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2025945,"threshold_uncertainty_score":0.8536351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01644236262300127,"score_gpt":0.2654557040079407,"score_spread":0.2490133413849394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}