{"id":"W1893872461","doi":"10.1002/eji.201445156","title":"Redirecting soluble antigen for MHC class I cross‐presentation during phagocytosis","year":2014,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation; Natural Sciences and Engineering Research Council of Canada; Tsinghua University","keywords":"Antigen processing; Endosome; MHC class I; Cross-presentation; Antigen presentation; Endocytosis; Biology; Cell biology; MHC class II; Antigen; Endocytic cycle; MHC restriction; Phagocytosis; CD74; Lysosome; Major histocompatibility complex; Transporter associated with antigen processing; Epitope; CD1; Antigen-presenting cell; T cell; Immune system; Immunology; Cell; Biochemistry; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001639184,0.0001986865,0.0002203854,0.00009245172,0.0001017751,0.0003940052,0.0001405089,0.000306482,0.0005867483],"category_scores_gemma":[0.0001211934,0.00009694081,0.0002030414,0.00006762365,0.0001801216,0.0002064662,0.0002004096,0.000340686,0.0002323195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002427676,"about_ca_system_score_gemma":0.0002094491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000277382,"about_ca_topic_score_gemma":0.0003259065,"domain_scores_codex":[0.9998473,0.00002653316,0.00000968,0.00002554099,0.00004080356,0.00005013747],"domain_scores_gemma":[0.9999199,0.00001679169,0.00002474795,0.00001420401,0.00001122767,0.00001312365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003412012,0.000006161071,0.0001310023,0.00001451224,0.000001611607,0.00003283297,0.000006855018,0.00001861442,0.9991471,0.00006285311,0.000008534131,0.0005358054],"study_design_scores_gemma":[0.00000734922,0.0001182326,0.002603694,0.000004229601,0.000007455079,0.0002334581,0.00001355322,0.0004966717,0.9955286,0.00004883915,0.0009356929,0.000002181182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952587,0.001245071,0.002659619,0.00004686117,0.00002037808,0.00001534045,0.00003055296,0.00002511162,0.0006983475],"genre_scores_gemma":[0.9966661,0.0007650409,0.001574625,0.00003855322,0.000009026045,0.000009685694,0.00004882851,0.00001006279,0.00087801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005867483,"threshold_uncertainty_score":0.001962841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01644236262300127,"score_gpt":0.2654557040079407,"score_spread":0.2490133413849394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}