{"id":"W1895360660","doi":"10.1093/genetics/163.3.973","title":"The Drosophila <i>chk2</i> Gene <i>loki</i> Is Essential for Embryonic DNA Double-Strand-Break Checkpoints Induced in S Phase or G2","year":2003,"lang":"en","type":"article","venue":"Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Biology; Checkpoint Kinase 2; Drosophila melanogaster; DNA damage; Cell cycle checkpoint; G2-M DNA damage checkpoint; Cell cycle; DNA replication; Cell biology; CHEK1; Genetics; DNA repair; DNA re-replication; DNA; Gene; Caenorhabditis elegans; Control of chromosome duplication","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005147347,0.0005811288,0.0001796228,0.0003493262,0.0002627476,0.0002431614,0.0002601408,0.0002533005,0.002579178],"category_scores_gemma":[0.00008654775,0.0001709802,0.0002503581,0.0001505295,0.0002095036,0.000189246,0.0003247088,0.0003986502,0.001346119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004472428,"about_ca_system_score_gemma":0.0002486942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001262702,"about_ca_topic_score_gemma":0.002062561,"domain_scores_codex":[0.999908,0.000008742981,0.000007937158,0.00003032759,0.00002455891,0.00002035574],"domain_scores_gemma":[0.9998803,0.00001424092,0.00005047584,0.00001180922,0.000007836179,0.00003528637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004135427,0.000007293867,0.0002979485,0.00003319067,0.000004528174,0.00006340512,0.000004233514,0.00003479006,0.998448,0.00007301268,0.00007568537,0.0009165401],"study_design_scores_gemma":[0.00003266175,0.0001359549,0.04515591,0.00002177855,0.00003255434,0.00113135,0.00003394329,0.001257674,0.9350601,0.00008437932,0.01703853,0.00001522097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819751,0.002692777,0.006097335,0.0001711746,0.00005713967,0.00003438166,0.003377252,0.0009213569,0.004673508],"genre_scores_gemma":[0.9836878,0.0005825091,0.003234318,0.0001100514,0.00001287065,0.00003995774,0.005151783,0.0001638992,0.007016907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002579178,"threshold_uncertainty_score":0.008628249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02119246489879198,"score_gpt":0.2928740983310145,"score_spread":0.2716816334322226,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}