{"id":"W1896032180","doi":"10.1002/mc.22227","title":"Cancer‐specific interruption of glucose metabolism by resveratrol is mediated through inhibition of Akt/GLUT1 axis in ovarian cancer cells","year":2014,"lang":"en","type":"article","venue":"Molecular Carcinogenesis","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Ministry of Education, Science and Technology; National Research Foundation of Korea; Canadian Institutes of Health Research; Western Carolina University","keywords":"GLUT1; Protein kinase B; Ovarian cancer; Biology; Glucose transporter; Apoptosis; Cancer cell; Resveratrol; Glucose uptake; Cancer research; Cancer; PI3K/AKT/mTOR pathway; Glucose Transporter Type 1; Endocrinology; Internal medicine; Pharmacology; Biochemistry; Insulin; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002792119,0.0003316571,0.0005802232,0.0001549162,0.00004310454,0.00001426199,0.0002413829,0.0003215007,0.00009733492],"category_scores_gemma":[0.00003794559,0.0003504856,0.0002869648,0.0004145206,0.0001464875,0.00001608376,0.0001119502,0.0001235774,0.00000296609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000544182,"about_ca_system_score_gemma":0.0001453108,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003715072,"about_ca_topic_score_gemma":0.0004647865,"domain_scores_codex":[0.9976965,0.0002485649,0.0006423384,0.0006450659,0.0003685563,0.0003990306],"domain_scores_gemma":[0.9986695,0.00001365862,0.0003350252,0.0006144051,0.0002626829,0.0001047215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002452392,0.0001114003,0.0005409243,0.00007825988,0.0001176515,0.000001742819,0.0003385636,0.0002182293,0.9921106,0.00007772355,0.002881078,0.003278641],"study_design_scores_gemma":[0.001748729,0.00009650515,0.002452819,0.00005666167,0.0001179627,0.000002195171,0.0000586405,0.00006146806,0.9416637,0.00005404595,0.0533753,0.0003119821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9428695,0.04953876,0.00546918,0.0001887787,0.0008096287,0.0003637957,0.0005880915,0.00001031658,0.0001618767],"genre_scores_gemma":[0.9843243,0.01367719,0.0004843518,0.0005592309,0.0004208574,0.0001495442,0.0002528775,0.00006390487,0.00006768701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05049422,"threshold_uncertainty_score":0.9998947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01262194714976614,"score_gpt":0.2507395676488516,"score_spread":0.2381176204990855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}