{"id":"W1896874692","doi":"10.4049/jimmunol.0800205","title":"Complement Factor H, a Marker of Self Protects against Experimental Autoimmune Encephalomyelitis","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Experimental autoimmune encephalomyelitis; Microglia; Immunology; Neuroinflammation; Complement system; Myelin oligodendrocyte glycoprotein; Biology; Innate immune system; Inflammation; Neuroscience; Encephalomyelitis; Neuroprotection; Immune system; Multiple sclerosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005413103,0.0002294087,0.0005846134,0.0001860937,0.0001741241,0.000008421521,0.0007893911,0.0001163021,0.001576888],"category_scores_gemma":[0.0000754664,0.0001552617,0.0002191268,0.0001332077,0.0002685693,0.000112511,0.0001427805,0.0003639106,0.00006235108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001257182,"about_ca_system_score_gemma":0.000138224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002983298,"about_ca_topic_score_gemma":0.000001864432,"domain_scores_codex":[0.997427,0.0008699376,0.001064587,0.0001299063,0.00010581,0.0004027132],"domain_scores_gemma":[0.9980658,0.0002360441,0.001019675,0.0004430719,0.0002133932,0.0000220493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007618527,0.0005229785,0.0004284538,0.00001231416,0.0007214735,0.00001109452,0.002264775,0.00000623224,0.98908,0.0003994745,0.001115212,0.004676161],"study_design_scores_gemma":[0.006581329,0.004973684,0.4176127,0.0003418784,0.0001537726,0.00128603,0.005124377,0.0000060908,0.5370473,0.0003510221,0.02613234,0.0003894656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9739497,0.02363974,0.00007652857,0.0005339728,0.0007470504,0.0005209916,0.00003334972,0.00003319441,0.000465442],"genre_scores_gemma":[0.9992821,0.0002338011,0.0001496004,0.0001403155,0.00004071777,0.000008574486,0.00001043997,0.00001232141,0.0001221195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4520327,"threshold_uncertainty_score":0.9993358,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01627536832739358,"score_gpt":0.2636640657627129,"score_spread":0.2473886974353193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}