{"id":"W1896874692","doi":"10.4049/jimmunol.0800205","title":"Complement Factor H, a Marker of Self Protects against Experimental Autoimmune Encephalomyelitis","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Experimental autoimmune encephalomyelitis; Microglia; Immunology; Neuroinflammation; Complement system; Myelin oligodendrocyte glycoprotein; Biology; Innate immune system; Inflammation; Neuroscience; Encephalomyelitis; Neuroprotection; Immune system; Multiple sclerosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002228585,0.0004970071,0.0003018634,0.000439445,0.0001426914,0.0002343976,0.0001835455,0.0004437947,0.001072711],"category_scores_gemma":[0.000128695,0.00009973839,0.0002100146,0.0001502843,0.0002288178,0.0002142766,0.0001482541,0.0007150219,0.0002373912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000206711,"about_ca_system_score_gemma":0.0002139087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009532614,"about_ca_topic_score_gemma":0.001140655,"domain_scores_codex":[0.9998198,0.00003215529,0.00002124861,0.00003547744,0.0000473789,0.00004388473],"domain_scores_gemma":[0.9999132,0.000009775771,0.00001986668,0.00001344996,0.00001787392,0.00002573525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003443861,0.00006795886,0.000287778,0.00007388171,0.00001579295,0.00005585091,0.00001999975,0.0000247469,0.9954435,0.00007905447,0.0001064812,0.003480625],"study_design_scores_gemma":[0.00006171674,0.001915539,0.01302276,0.00003812832,0.00005612196,0.0006356908,0.00004517847,0.0006583175,0.9786754,0.0001444213,0.004737353,0.000009396862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832467,0.009387588,0.003266341,0.0002781518,0.0001808415,0.00007672158,0.0003975671,0.0002196728,0.002946342],"genre_scores_gemma":[0.992444,0.002107754,0.001643682,0.0001201353,0.0000487313,0.000044236,0.0004161487,0.00001647351,0.00315882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001072711,"threshold_uncertainty_score":0.003588557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01627536832739358,"score_gpt":0.2636640657627129,"score_spread":0.2473886974353193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}