{"id":"W1897454326","doi":"10.4049/jimmunol.1300774","title":"The Human Immune System Recognizes Neopeptides Derived from Mitochondrial DNA Deletions","year":2014,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; York University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Immune system; Mitochondrial DNA; CD8; Major histocompatibility complex; Human leukocyte antigen; Homology (biology); Mitochondrion; Cytotoxic T cell; Genetics; Amino acid; Gene; Molecular biology; Antigen; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001490807,0.0003740865,0.0002393074,0.0002015903,0.0001184812,0.0003130898,0.0001524247,0.0004920241,0.001411479],"category_scores_gemma":[0.0003542543,0.000112584,0.0002309405,0.0001012009,0.0001458627,0.0001677181,0.0002514813,0.0004534499,0.0007577752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007969741,"about_ca_system_score_gemma":0.00009960837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001166535,"about_ca_topic_score_gemma":0.0001420254,"domain_scores_codex":[0.9998572,0.00003220161,0.00001012767,0.00004228952,0.00003697781,0.00002121559],"domain_scores_gemma":[0.9998281,0.00008204947,0.00003515578,0.0000146511,0.00001992874,0.00002009329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001461891,0.00005122109,0.007948659,0.00009499527,0.00002026532,0.0001806528,0.0000303958,0.0008787278,0.9666367,0.0001104306,0.0001497654,0.02375187],"study_design_scores_gemma":[0.00009420992,0.003077736,0.0805759,0.00007780414,0.0001132936,0.005298172,0.0002619269,0.02709432,0.8641489,0.001654181,0.01756559,0.00003783952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9762201,0.002782314,0.01797137,0.0002586426,0.00004060218,0.00006136998,0.000287619,0.0001676554,0.002210159],"genre_scores_gemma":[0.9841484,0.001122675,0.013072,0.0002047397,0.00003204279,0.00002878844,0.0005665963,0.00001346239,0.000811259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001411479,"threshold_uncertainty_score":0.00472182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01054844994883425,"score_gpt":0.2295444917187839,"score_spread":0.2189960417699497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}