{"id":"W1897802257","doi":"10.1593/neo.91872","title":"Impact of Metronomic UFT/Cyclophosphamide Chemotherapy and Antiangiogenic Drug Assessed in a New Preclinical Model of Locally Advanced Orthotopic Hepatocellular Carcinoma","year":2010,"lang":"en","type":"article","venue":"Neoplasia","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Cancer Institute; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Sorafenib; Medicine; Hepatocellular carcinoma; Doxorubicin; Chemotherapy; Cyclophosphamide; Bevacizumab; Cancer research; Prodrug; Paclitaxel; Internal medicine; Oncology; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000235245,0.0005482412,0.0006361961,0.0004233911,0.0001482189,0.0003510959,0.000283429,0.0002882814,0.0009515047],"category_scores_gemma":[0.0001163507,0.0001307081,0.0003071929,0.0002119795,0.0002586902,0.0003479439,0.0001407449,0.0008453046,0.0001515904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004022685,"about_ca_system_score_gemma":0.0004403854,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001125231,"about_ca_topic_score_gemma":0.002091767,"domain_scores_codex":[0.9998537,0.00003172022,0.00001055123,0.00002899463,0.00003468085,0.00004022152],"domain_scores_gemma":[0.9998831,0.00001518799,0.00002686983,0.00001441817,0.000012161,0.00004832683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002835454,0.002377428,0.0003074231,0.0001327795,0.00003105935,0.0001211906,0.00003658126,0.0009244949,0.9866812,0.0001726521,0.0002170273,0.006162597],"study_design_scores_gemma":[0.0006084098,0.04099924,0.003257635,0.00001239456,0.0001257245,0.0003476228,0.00004652557,0.003431016,0.9480363,0.00006697395,0.003048443,0.00001986638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966577,0.001131716,0.0008560339,0.0001062488,0.00006303573,0.00009169878,0.0002397769,0.0000601264,0.0007936493],"genre_scores_gemma":[0.9951202,0.001192705,0.001728003,0.00004895992,0.00002238648,0.000125482,0.0005125158,0.00001556076,0.001234046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001125231,"threshold_uncertainty_score":0.003183067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02788122324249479,"score_gpt":0.2843794045145924,"score_spread":0.2564981812720976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}