{"id":"W1898276341","doi":"10.4049/jimmunol.0902575","title":"Regulation of Lentivirus Neurovirulence by Lipopolysaccharide Conditioning: Suppression of CXCL10 in the Brain by IL-10","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of Calgary; University of Alberta Hospital; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Lentivirus; Vector (molecular biology); Virology; Biology; Human immunodeficiency virus (HIV); Genetics; Gene; Recombinant DNA; Viral disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001325611,0.0004229755,0.0001853551,0.0001919487,0.00009702904,0.0002308892,0.0001772053,0.0002392505,0.0009733903],"category_scores_gemma":[0.0001054151,0.00009302078,0.0002210021,0.00007450143,0.000299929,0.0001909604,0.0001608672,0.0005587315,0.0001315865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002500542,"about_ca_system_score_gemma":0.0001926178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005021053,"about_ca_topic_score_gemma":0.0006830052,"domain_scores_codex":[0.9999162,0.00001422172,0.000007722482,0.0000136448,0.00001276493,0.00003537713],"domain_scores_gemma":[0.9999157,0.000009745729,0.00002439549,0.000008200185,0.000009115354,0.00003279874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000356939,0.00005832001,0.0001609351,0.00002349867,0.000003526504,0.0000395493,0.00001147791,0.00001913612,0.99866,0.00002402605,0.00001471201,0.0006278647],"study_design_scores_gemma":[0.00004156329,0.001336472,0.008826179,0.00001147585,0.0000173876,0.0002229749,0.00005025035,0.0005768492,0.988474,0.00005444692,0.0003835852,0.000004804115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987139,0.0003536003,0.0004147114,0.00003782716,0.00001144878,0.00001660633,0.0001227755,0.00002328582,0.0003058384],"genre_scores_gemma":[0.997575,0.0003259099,0.0008513129,0.00003276833,0.000007556516,0.00006184921,0.0002431202,0.000006089646,0.0008963916],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009733903,"threshold_uncertainty_score":0.003256381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01090486291571386,"score_gpt":0.2632246496841391,"score_spread":0.2523197867684253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}