{"id":"W1899067258","doi":"10.1139/y11-124","title":"Folic acid supplementation attenuates high fat diet induced hepatic oxidative stress via regulation of NADPH oxidase","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada; University of Manitoba; University of Winnipeg; St. Boniface Hospital","funders":"Canadian Institutes of Health Research; Manitoba Health Research Council; Heart and Stroke Foundation of Canada","keywords":"Oxidative stress; NADPH oxidase; Endocrinology; Internal medicine; Lipid peroxidation; Liver injury; Antioxidant; Oxidase test; Hyperhomocysteinemia; Oxidative phosphorylation; Chemistry; Biology; Biochemistry; Homocysteine; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002193553,0.0001065952,0.0003225241,0.0003037704,0.0000882405,0.000003022237,0.00007174187,0.0001162172,0.002456624],"category_scores_gemma":[0.00003427902,0.00008886428,0.0000521757,0.0001413365,0.000183969,0.000179379,0.0000137759,0.0002669616,0.000008482423],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000760286,"about_ca_system_score_gemma":0.0002551378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001847281,"about_ca_topic_score_gemma":0.001000026,"domain_scores_codex":[0.9989502,0.0002199807,0.0003114226,0.00009513918,0.00008682888,0.0003364516],"domain_scores_gemma":[0.9989267,0.000108945,0.0002212259,0.00006595652,0.0002343816,0.0004427828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004867699,0.00007297625,0.02107953,0.0001061433,0.0002569227,0.00001667633,0.0007897936,0.00000414407,0.9741198,0.00005800288,0.001679655,0.001329526],"study_design_scores_gemma":[0.001578783,0.001334633,0.2070088,0.00002524657,0.0001665191,0.00005167663,0.0001377817,0.00005019068,0.7891126,0.0002711096,0.0001980381,0.00006465647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980887,0.0004153367,0.00001642121,0.0008456629,0.0003669644,0.0001824645,0.00004325747,0.000001925104,0.00003929729],"genre_scores_gemma":[0.9989498,0.00006659062,0.00008589775,0.0003454805,0.0004058359,0.000005671677,0.00008174617,0.000009376849,0.00004958246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1859293,"threshold_uncertainty_score":0.9984553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02731063228362893,"score_gpt":0.3309304414642032,"score_spread":0.3036198091805742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}