{"id":"W1899463496","doi":"10.1089/vim.2014.0094","title":"A Lower Viral Set Point but Little Immunological Impact After Early Treatment During Primary HIV Infection","year":2015,"lang":"en","type":"article","venue":"Viral Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Rijksinstituut voor Volksgezondheid en Milieu; Stichting Sanquin Bloedvoorziening; Universiteit van Amsterdam; Aids Fonds","keywords":"Perforin; Immunology; CD8; Cart; Immune system; Cytolysis; Granzyme B; T cell; Medicine; Viral load; Granzyme A; Cytotoxic T cell; Granzyme; Biology; Virology; Virus; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007410249,0.0002815032,0.001233405,0.0001096946,0.0002337662,0.0004770838,0.000200688,0.0005268463,0.002696269],"category_scores_gemma":[0.001067289,0.0001402622,0.0004412559,0.0001111428,0.0003812455,0.0002451046,0.0002133987,0.0007635895,0.0001683521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001903685,"about_ca_system_score_gemma":0.0003179007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002327103,"about_ca_topic_score_gemma":0.0005522385,"domain_scores_codex":[0.9996159,0.0002059744,0.00001679221,0.00004751221,0.00003719632,0.00007656532],"domain_scores_gemma":[0.9992827,0.0002307621,0.0001242978,0.00005489105,0.00003156544,0.0002758965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7070789,0.01556591,0.02757657,0.001021098,0.001006215,0.0004273423,0.0002978476,0.0007571367,0.0381561,0.0002469052,0.000956955,0.2069091],"study_design_scores_gemma":[0.1081515,0.6764358,0.2027567,0.0001614688,0.0008748074,0.0006377258,0.0001572805,0.0006118137,0.00703922,0.0003596638,0.00278112,0.00003293887],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980474,0.001232843,0.00005267119,0.00007256856,0.00003588535,0.00004872873,0.00003114267,0.000005633975,0.0004731546],"genre_scores_gemma":[0.9990062,0.0002702121,0.00008471777,0.0001496584,0.00006245518,0.0000414942,0.00004452064,0.000001478573,0.000339454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002696269,"threshold_uncertainty_score":0.009019911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01813134011997188,"score_gpt":0.2702168477696677,"score_spread":0.2520855076496958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}