{"id":"W1900158970","doi":"10.1186/s12916-015-0470-9","title":"A proposed panel of biomarkers of healthy ageing","year":2015,"lang":"en","type":"article","venue":"BMC Medicine","topic":"GDF15 and Related Biomarkers","field":"Medicine","cited_by":234,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Economic and Social Research Council; Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Medical Research Council; Chief Scientist Office, Scottish Government Health and Social Care Directorate; Directorate for Biological Sciences; Centre for Cognitive Ageing and Cognitive Epidemiology; Scottish Government; University of Toronto; University of Glasgow; University of Edinburgh; National Institute for Health and Care Research; Universitetet i Oslo; McGill University; National Heart, Lung, and Blood Institute; Northwestern University; University of Dundee; Public Health Agency; Office of Research and Development","keywords":"Ageing; Medicine; Cognition; Function (biology); Cognitive decline; Healthy ageing; Gerontology; Dementia; Physical medicine and rehabilitation; Pathology; Disease; Psychiatry; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03405983,0.004072384,0.003407405,0.01065595,0.001714308,0.005960252,0.00354368,0.004110406,0.00531533],"category_scores_gemma":[0.05282375,0.0008555994,0.004855894,0.006242152,0.002034531,0.005241476,0.00546678,0.004387645,0.003190581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002841611,"about_ca_system_score_gemma":0.007480787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003324058,"about_ca_topic_score_gemma":0.002805492,"domain_scores_codex":[0.9824206,0.006472345,0.003121109,0.003205483,0.003959885,0.0008206454],"domain_scores_gemma":[0.9527912,0.01579196,0.006103163,0.002266789,0.02147735,0.001569449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001346766,0.0003973107,0.2460242,0.01533846,0.004101059,0.0007802451,0.001907315,0.007729439,0.004681402,0.04578424,0.05490751,0.6170021],"study_design_scores_gemma":[0.0007430922,0.005000605,0.3274232,0.0217511,0.01104452,0.005117228,0.002548633,0.02596698,0.008182114,0.2205489,0.3708303,0.0008433846],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.08748895,0.2669994,0.3926349,0.1468368,0.01071586,0.007726592,0.03128785,0.002970059,0.0533395],"genre_scores_gemma":[0.4744149,0.04839668,0.4228558,0.0184427,0.00368583,0.00759639,0.0189321,0.0001351588,0.005540458],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.03405983,"threshold_uncertainty_score":0.1801278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1234177466460365,"score_gpt":0.3319616974754278,"score_spread":0.2085439508293912,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}