{"id":"W1900770269","doi":"10.1002/pro.492","title":"Förster resonance energy transfer measurements of cofactor‐dependent effects on protein arginine <i>N</i>‐methyltransferase homodimerization","year":2010,"lang":"en","type":"article","venue":"Protein Science","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; University of British Columbia; Canada Research Chairs","keywords":"Förster resonance energy transfer; Cofactor; Chemistry; Methyltransferase; Methylation; Arginine; Methionine; Stereochemistry; Fluorescence; Dissociation constant; Enzyme; Biochemistry; Biophysics; Amino acid; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007116022,0.0007917631,0.0006063863,0.0002196759,0.0004317916,0.0004010597,0.0008824941,0.001270062,0.001679027],"category_scores_gemma":[0.001095507,0.0002579454,0.0004912452,0.0003609978,0.0004195293,0.0005918076,0.0004886886,0.001572115,0.0005800622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001026782,"about_ca_system_score_gemma":0.0002159486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009923299,"about_ca_topic_score_gemma":0.001119208,"domain_scores_codex":[0.9990752,0.00022839,0.00003986986,0.000262248,0.0002287902,0.0001654526],"domain_scores_gemma":[0.9993355,0.0002829718,0.0001400111,0.00006565368,0.0001060904,0.0000697248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004628529,0.00002054172,0.00009809948,0.00002883143,0.000006180472,0.00001948579,0.00004101236,0.00007112259,0.9989954,0.00006345641,0.00004699701,0.000562575],"study_design_scores_gemma":[0.000004393589,0.00004305712,0.0004953205,0.000001927282,0.000004598106,0.00003506179,0.00002353304,0.001025906,0.9980463,0.00002667147,0.0002879439,0.000005302148],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.966942,0.001636875,0.0275407,0.0002241036,0.00005974805,0.00006123952,0.0004325974,0.0003599926,0.002742809],"genre_scores_gemma":[0.9775519,0.001230519,0.01728662,0.0001458156,0.00001346603,0.0001243024,0.0004695901,0.00006114603,0.003116647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001679027,"threshold_uncertainty_score":0.007449865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009527115603705338,"score_gpt":0.2354904294768458,"score_spread":0.2259633138731404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}