{"id":"W1900801624","doi":"10.4049/jimmunol.1401065","title":"The N-Terminal Domain of NLRC5 Confers Transcriptional Activity for MHC Class I and II Gene Expression","year":2014,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"CIITA; MHC class I; CD74; Biology; MHC class II; CD8; Major histocompatibility complex; Antigen processing; Cell biology; Cytotoxic T cell; Gene; Genetics; Immune system; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001762719,0.0002544968,0.0002291306,0.0001296926,0.0001263716,0.0002546769,0.000166178,0.0003253459,0.001851917],"category_scores_gemma":[0.0002444399,0.00007886525,0.0004078804,0.0001147285,0.000223862,0.0002168376,0.0001605936,0.0004252262,0.0007927476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004130194,"about_ca_system_score_gemma":0.0002274275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003925914,"about_ca_topic_score_gemma":0.0004613299,"domain_scores_codex":[0.9997777,0.0000497337,0.000024497,0.00004693811,0.00005594216,0.00004516375],"domain_scores_gemma":[0.9998181,0.00003650072,0.00004647475,0.00004191187,0.00002014887,0.00003680858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004648299,0.000007943199,0.0002090687,0.00003848654,0.000003073055,0.00003396973,0.000007162067,0.00006665433,0.9981157,0.0001086353,0.00003677458,0.001326058],"study_design_scores_gemma":[0.00001835403,0.0001629659,0.006169441,0.00001312982,0.00001529209,0.0009451422,0.00002470947,0.001169706,0.9823902,0.00006443973,0.009020283,0.00000623451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9713878,0.003742541,0.0184447,0.0001981649,0.00006757653,0.00005133147,0.000878614,0.0001836596,0.005045523],"genre_scores_gemma":[0.9885428,0.0003408523,0.007472618,0.00006654634,0.00001021981,0.0000186344,0.001488507,0.00001991653,0.002039829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001851917,"threshold_uncertainty_score":0.006195307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01166286171628705,"score_gpt":0.2416064902136327,"score_spread":0.2299436284973456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}