{"id":"W1902811474","doi":"10.7554/elife.07025","title":"A mex3 homolog is required for differentiation during planarian stem cell lineage development","year":2015,"lang":"en","type":"article","venue":"eLife","topic":"Planarian Biology and Electrostimulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Ontario Institute for Cancer Research; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Hospital for Sick Children; Ontario Institute for Cancer Research","keywords":"Planarian; Biology; Progenitor cell; Stem cell; Cell biology; RNA interference; Cellular differentiation; Progenitor; Regeneration (biology); Cell fate determination; Regulator; Developmental biology; Cell; Compartment (ship); Genetics; RNA; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006746185,0.0002196436,0.0001409539,0.0002029206,0.0001971252,0.0002296098,0.0001605423,0.0001765919,0.001049937],"category_scores_gemma":[0.0001140772,0.0001419252,0.0001701962,0.0001458711,0.0002617183,0.0001469693,0.0002740797,0.0004496828,0.0004427968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002935477,"about_ca_system_score_gemma":0.0002707986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00115347,"about_ca_topic_score_gemma":0.002289506,"domain_scores_codex":[0.999911,0.000007191706,0.000006265298,0.00001937972,0.00003511892,0.00002093939],"domain_scores_gemma":[0.9998891,0.00001587795,0.00004103806,0.000009094455,0.00001158078,0.00003336839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002218357,0.000001626423,0.0002889269,0.000009606268,0.000001127825,0.00004193545,0.000008026911,0.00001748992,0.9989736,0.00003464867,0.00001088426,0.0005900054],"study_design_scores_gemma":[0.000005935063,0.00003882239,0.03188554,0.000004644874,0.00001075026,0.0003731915,0.00005145226,0.0005772724,0.9647007,0.00007045338,0.002275885,0.000005315243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994243,0.0006799903,0.003289694,0.00007899386,0.000008732576,0.000008676287,0.0005326507,0.0001599413,0.0009983127],"genre_scores_gemma":[0.9954748,0.0003230365,0.001404468,0.00003656134,0.000002347792,0.00001247804,0.0006595564,0.00004331951,0.002043477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00115347,"threshold_uncertainty_score":0.003512383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02356927351958578,"score_gpt":0.2414295498581513,"score_spread":0.2178602763385655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}