{"id":"W1903184423","doi":"10.1007/bf03403754","title":"Newborn Screening for MCAD Deficiency","year":2008,"lang":"en","type":"article","venue":"Canadian Journal of Public Health","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's & Women's Health Centre of British Columbia; BC Children's Hospital","funders":"","keywords":"Newborn screening; Medicine; Incidence (geometry); Acyl CoA dehydrogenase; Carnitine; Internal medicine; Pediatrics; Dried blood spot; Gastroenterology; Dehydrogenase; Biology; Genetics; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008576157,0.00008359854,0.0001553468,0.0001516688,0.0002460305,0.0000229744,0.0002315172,0.00006503598,0.00003114187],"category_scores_gemma":[0.0004260223,0.00007941672,0.00009721902,0.0001180194,0.00008588845,0.000006217924,0.000007408793,0.00007699925,0.000001722912],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001355177,"about_ca_system_score_gemma":0.006605915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001363557,"about_ca_topic_score_gemma":0.008642778,"domain_scores_codex":[0.9988893,0.00006451606,0.000312004,0.0001223552,0.00009991532,0.0005119423],"domain_scores_gemma":[0.9982299,0.000009218914,0.0001772838,0.0001489025,0.0002207071,0.001213944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002109752,0.00005634528,0.06771618,0.00005855412,0.00007534176,0.00002147818,0.001194411,0.0001745381,0.0007388577,0.001705804,0.2209665,0.7072709],"study_design_scores_gemma":[0.0005011951,0.0002665523,0.02991093,0.000005896221,0.000003084609,0.0001592276,0.0003022054,0.0000133808,0.00007783634,0.00006053985,0.9686142,0.00008496293],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6038146,0.02107048,0.3607511,0.01092559,0.0007729133,0.0002749986,0.00007848636,0.000003547,0.002308302],"genre_scores_gemma":[0.9640246,0.0007482567,0.03019004,0.003771838,0.000518441,0.00000405274,0.00003950462,0.00002296941,0.0006802829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7476477,"threshold_uncertainty_score":0.9990257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06716754668214187,"score_gpt":0.2916052755033818,"score_spread":0.2244377288212399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}