{"id":"W1904302180","doi":"10.1096/fasebj.28.1_supplement.847.2","title":"Characterizing and treating pulmonary pathology in Marfan syndrome (847.2)","year":2014,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of British Columbia","funders":"","keywords":"Sildenafil; Losartan; Medicine; cGMP-specific phosphodiesterase type 5; Marfan syndrome; Pulmonary artery; Lung; Pulmonary hypertension; Cardiology; Pathogenesis; Internal medicine; Angiotensin II; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004127875,0.0003452112,0.0003822132,0.0003491016,0.0001921388,0.0002326873,0.0001779191,0.0005117245,0.0006688515],"category_scores_gemma":[0.0002475428,0.00008264503,0.0002745942,0.0000881019,0.0002118228,0.0001715035,0.0002165393,0.0005151522,0.0001810075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001676727,"about_ca_system_score_gemma":0.0003358046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003183174,"about_ca_topic_score_gemma":0.0006935027,"domain_scores_codex":[0.9999073,0.00002241155,0.000009752888,0.00001309458,0.00002182697,0.00002567746],"domain_scores_gemma":[0.9999013,0.00001384016,0.00003057633,0.000004663026,0.00001162211,0.000037883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001900157,0.001244447,0.0332885,0.000761612,0.0001127059,0.01371335,0.0001868233,0.0004526118,0.7052956,0.000879962,0.003546293,0.238618],"study_design_scores_gemma":[0.002406162,0.03201719,0.4226713,0.0009981936,0.0007490006,0.1331044,0.0006345994,0.004617868,0.3286033,0.002356477,0.07174899,0.00009239775],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9620429,0.0232901,0.006990201,0.003077861,0.0002410414,0.0002196493,0.00009791237,0.0001602303,0.00388015],"genre_scores_gemma":[0.9773042,0.009339901,0.01001151,0.001007276,0.0004403775,0.00008859131,0.0001622416,0.00001513041,0.001630857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006688515,"threshold_uncertainty_score":0.002237558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02156178842063644,"score_gpt":0.2715606671486491,"score_spread":0.2499988787280126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}