{"id":"W1905377432","doi":"10.1093/ajh/hpv144","title":"Interactive Effect of the KCNJ11 Ile337Val Polymorphism and Cigarette Smoking on the Antihypertensive Response to Irbesartan in Chinese Hypertensive Patients","year":2015,"lang":"en","type":"article","venue":"American Journal of Hypertension","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Anhui Medical University; National Natural Science Foundation of China","keywords":"Irbesartan; Medicine; Internal medicine; Pharmacology; Population; Blood pressure; Endocrinology; Genotype; Gene; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005208733,0.0001661512,0.000359649,0.0001126128,0.00005316097,0.000008538294,0.0001614346,0.00005175948,0.000001116247],"category_scores_gemma":[0.0007912674,0.00008156718,0.0001165226,0.0002355271,0.000171222,0.00001276212,0.00005630463,0.0001798354,4.793674e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002572185,"about_ca_system_score_gemma":0.00005579242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004392616,"about_ca_topic_score_gemma":0.000008247912,"domain_scores_codex":[0.9986825,0.0003748254,0.0003107687,0.0001714408,0.0003096465,0.0001508337],"domain_scores_gemma":[0.9986908,0.0001523519,0.0003453184,0.0002074349,0.0005085095,0.0000955397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.02854292,0.0002112049,0.2552918,0.000008437436,0.0002360813,0.0001030932,0.002216358,0.0004654627,0.700316,0.000005187013,0.001375458,0.01122797],"study_design_scores_gemma":[0.002814026,0.008434195,0.8617283,0.0002591414,0.000100018,0.0002678602,0.001500349,0.00009599307,0.1242021,0.00002588679,0.0003564674,0.0002156479],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970378,0.0001101181,0.00001040164,0.002303011,0.0003210834,0.0001980745,0.000005166552,0.000001496582,0.00001290869],"genre_scores_gemma":[0.9982105,0.00001752965,0.00001520274,0.001628872,0.00009102256,0.000002380203,0.000003764612,0.00001743872,0.00001324639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6064365,"threshold_uncertainty_score":0.3326213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007858866455143339,"score_gpt":0.2218587775976198,"score_spread":0.2139999111424764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}