{"id":"W1905620693","doi":"10.4049/jimmunol.168.2.713","title":"IL-1β Enhances CD40 Ligand-Mediated Cytokine Secretion by Human Dendritic Cells (DC): A Mechanism for T Cell-Independent DC Activation","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research & Development Corporation","funders":"","keywords":"CD40; Dendritic cell; Cytokine; Cell biology; T cell; Secretion; Biology; Priming (agriculture); Monocyte; Immune system; Antigen-presenting cell; Interleukin 15; Immunology; Chemistry; Interleukin; Cytotoxic T cell; Endocrinology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009419998,0.0003287499,0.0005822149,0.0002813647,0.0006254661,0.00003149515,0.0006913273,0.0004999202,0.0007622404],"category_scores_gemma":[0.0001571284,0.0002387453,0.0002551514,0.0001805143,0.000325542,0.0002704427,0.0000686997,0.0008100775,0.0002022953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001238526,"about_ca_system_score_gemma":0.0000580309,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000514578,"about_ca_topic_score_gemma":0.000005321584,"domain_scores_codex":[0.9973159,0.0008658234,0.00093034,0.0002075875,0.0001046912,0.0005757005],"domain_scores_gemma":[0.9973139,0.000928282,0.001006399,0.0003709313,0.0003572962,0.0000232145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001839,0.0003901255,0.000003294596,0.00001796855,0.0005625842,0.000003314359,0.001297893,0.00000344349,0.9912312,0.0003483383,0.003325664,0.0009771849],"study_design_scores_gemma":[0.004478596,0.002718024,0.00009999206,0.0000776764,0.0001551548,0.0004006278,0.001023566,0.00001028231,0.973519,0.0007076539,0.01656049,0.0002489388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791973,0.01326583,0.004181918,0.001151877,0.001509983,0.0004602057,0.00005281086,0.00004075892,0.0001393569],"genre_scores_gemma":[0.9897165,0.005427139,0.00005079562,0.0003929418,0.00008531955,0.00002525537,0.00006015704,0.00004397277,0.004197913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01771219,"threshold_uncertainty_score":0.9735752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01125502372857098,"score_gpt":0.2304455187097784,"score_spread":0.2191904949812074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}