{"id":"W1905620693","doi":"10.4049/jimmunol.168.2.713","title":"IL-1β Enhances CD40 Ligand-Mediated Cytokine Secretion by Human Dendritic Cells (DC): A Mechanism for T Cell-Independent DC Activation","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research & Development Corporation","funders":"","keywords":"CD40; Dendritic cell; Cytokine; Cell biology; T cell; Secretion; Biology; Priming (agriculture); Monocyte; Immune system; Antigen-presenting cell; Interleukin 15; Immunology; Chemistry; Interleukin; Cytotoxic T cell; Endocrinology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001599156,0.0005862785,0.0002633578,0.0002220259,0.00009181476,0.0004015886,0.0001153428,0.0002528059,0.001320199],"category_scores_gemma":[0.0001354769,0.0001195083,0.000362667,0.0001643317,0.0001460418,0.0001763112,0.0001870634,0.0006031765,0.0005361261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003139563,"about_ca_system_score_gemma":0.0002213689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001928118,"about_ca_topic_score_gemma":0.0002045557,"domain_scores_codex":[0.9998119,0.000035743,0.0000171351,0.00003468245,0.00003824056,0.00006223752],"domain_scores_gemma":[0.9999053,0.0000186494,0.00002212613,0.00001171357,0.00001575422,0.00002636099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001571302,0.00004593594,0.0001430636,0.00008277227,0.000003171714,0.00007134558,0.00002132802,0.00003230117,0.9972567,0.00004427257,0.00005486064,0.002087141],"study_design_scores_gemma":[0.00007176843,0.0004085901,0.002396315,0.00001838528,0.00001739158,0.0003542603,0.00001747301,0.0003332677,0.9932953,0.0000648009,0.003019095,0.000003351799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792584,0.009759202,0.006482571,0.0004334592,0.0002332872,0.0001685525,0.0007081022,0.0001581511,0.002798364],"genre_scores_gemma":[0.9883658,0.004637769,0.003577557,0.0001949905,0.00009380746,0.00009772495,0.0004512624,0.00002511944,0.002555998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001320199,"threshold_uncertainty_score":0.004416525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01125502372857098,"score_gpt":0.2304455187097784,"score_spread":0.2191904949812074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}