{"id":"W1909039063","doi":"10.1186/2050-5736-3-s1-p20","title":"Mouse positioning device for blood brain barrier FUS exposure","year":2015,"lang":"en","type":"article","venue":"Journal of Therapeutic Ultrasound","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Thunder Bay Regional Research Institute","funders":"Focused Ultrasound Foundation","keywords":"Enzyme replacement therapy; Medicine; Glucocerebroside; Blood–brain barrier; Gaucher's disease; Positron emission tomography; Glucocerebrosidase; Enzyme; Disease; Central nervous system; Pathology; Internal medicine; Radiology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001065874,0.0001556714,0.0003671823,0.0001745749,0.0001005353,0.00007923774,0.0002073541,0.0001175728,0.0001329904],"category_scores_gemma":[0.001061287,0.0001211548,0.0002424309,0.0001973615,0.00007286397,0.0002079435,0.00001545191,0.0003594623,0.00001298125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001511186,"about_ca_system_score_gemma":0.0004190358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001331402,"about_ca_topic_score_gemma":0.000007035358,"domain_scores_codex":[0.9982617,0.0001109989,0.0004514179,0.0001443716,0.000699612,0.0003318575],"domain_scores_gemma":[0.9976543,0.0005914553,0.0002401036,0.0002114246,0.0009029285,0.000399816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00356341,0.001149984,0.03965066,0.000183659,0.002208966,0.0002099644,0.004348691,0.0001034703,0.9343113,0.0002278057,0.006519324,0.007522804],"study_design_scores_gemma":[0.1161372,0.04404161,0.05439711,0.001238517,0.006286844,0.04078955,0.02447363,0.0004626381,0.3849259,0.01669431,0.3081725,0.002380232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871117,0.00552161,0.002765141,0.00318099,0.0002153927,0.0004006078,0.00001206151,0.00001737729,0.0007751345],"genre_scores_gemma":[0.9917823,0.00006363209,0.003096408,0.002265778,0.0005071016,0.00000946086,0.000007835768,0.00004538166,0.002222077],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5493853,"threshold_uncertainty_score":0.494055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05041694567237225,"score_gpt":0.3361619329985708,"score_spread":0.2857449873261985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}