{"id":"W1909573815","doi":"10.4049/jimmunol.164.4.1783","title":"Activation of Macrophage CD8: Pharmacological Studies of TNF and IL-1β Production","year":2000,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Dalhousie University","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Syk; Tumor necrosis factor alpha; CD8; Biology; Secretion; Cell biology; Tyrosine kinase; Molecular biology; Chemistry; Signal transduction; Immunology; Endocrinology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001886204,0.0003333776,0.0001961357,0.0001617564,0.0001339706,0.0001989007,0.0001205241,0.0002055487,0.001224558],"category_scores_gemma":[0.000119523,0.00008870634,0.0001698755,0.0001338931,0.0001464885,0.0001920363,0.0001505624,0.0005622405,0.0002891363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001964855,"about_ca_system_score_gemma":0.0001165426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001473279,"about_ca_topic_score_gemma":0.0002135792,"domain_scores_codex":[0.9998463,0.00003428914,0.00001542145,0.00001898184,0.00002815321,0.0000569202],"domain_scores_gemma":[0.999929,0.00001464895,0.0000164876,0.000006329171,0.00001311017,0.00002047341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002339809,0.00005484922,0.00009247695,0.00004609672,0.000002124109,0.00003444116,0.00001136005,0.00001682729,0.9983689,0.00004030148,0.00001436392,0.00108431],"study_design_scores_gemma":[0.00006592536,0.00105067,0.002550535,0.000008276746,0.00001637419,0.000283514,0.00002752421,0.0002869033,0.993682,0.00004705437,0.001978428,0.00000265025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919183,0.003346235,0.00244133,0.0001468568,0.0000455288,0.00004614176,0.0001456273,0.00002197687,0.001888021],"genre_scores_gemma":[0.9934354,0.001904106,0.002750751,0.00006811695,0.00003786561,0.00008836857,0.0001523938,0.000008734267,0.001554316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001224558,"threshold_uncertainty_score":0.004096508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02379316761464346,"score_gpt":0.2835165557756154,"score_spread":0.2597233881609719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}