{"id":"W1910098042","doi":"10.1039/c5ob01151e","title":"Efficient one-pot synthesis of 5-perfluoroalkylpyrazoles by cyclization of hydrazone dianions","year":2015,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Alkaline Phosphatase Research Studies","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Alkaline phosphatase; Hydrazone; Hydrazine (antidepressant); Phosphatase; Pyrazole; Phosphodiesterase; Combinatorial chemistry; Enzyme; Stereochemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002723376,0.0001865375,0.0004462048,0.00004981665,0.00003991671,0.000006020675,0.0001685359,0.000119483,0.0001751562],"category_scores_gemma":[0.001479399,0.0001775371,0.0001079841,0.0004856389,0.0002834922,0.00001745635,0.0001606444,0.0001205934,0.00001823831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000127443,"about_ca_system_score_gemma":0.0002832766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004651986,"about_ca_topic_score_gemma":8.910276e-7,"domain_scores_codex":[0.9983008,0.00002810358,0.0004032909,0.0002959922,0.0006941694,0.0002776628],"domain_scores_gemma":[0.9985984,0.00006360888,0.0001772047,0.0005201811,0.0003794736,0.0002611614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006851834,0.0006273534,0.0004432429,0.0005016206,0.0002272295,0.00001841759,0.0001129558,0.000001800438,0.9959433,0.000008318488,0.001512301,0.0005349499],"study_design_scores_gemma":[0.0007619315,0.00006619551,0.0001790392,0.0002325797,0.0002006847,0.00002177352,0.0003158435,0.0002750561,0.9975264,0.00001792995,0.0002628576,0.0001396802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9336306,0.02335017,0.03629906,0.002281538,0.00005951102,0.000612433,0.0004488681,0.0001226779,0.003195119],"genre_scores_gemma":[0.9987724,0.0002995965,0.0005040618,0.00003146242,0.00003931343,0.00001641387,0.0001669155,0.00003962428,0.0001302477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06514174,"threshold_uncertainty_score":0.7239754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01521935179073645,"score_gpt":0.2678955962389002,"score_spread":0.2526762444481638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}