{"id":"W1910098042","doi":"10.1039/c5ob01151e","title":"Efficient one-pot synthesis of 5-perfluoroalkylpyrazoles by cyclization of hydrazone dianions","year":2015,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Alkaline Phosphatase Research Studies","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Alkaline phosphatase; Hydrazone; Hydrazine (antidepressant); Phosphatase; Pyrazole; Phosphodiesterase; Combinatorial chemistry; Enzyme; Stereochemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000281681,0.0005369853,0.0003249107,0.0002650662,0.0001860406,0.0001159376,0.0004325022,0.000440499,0.00187741],"category_scores_gemma":[0.0002114892,0.0001839373,0.0003177986,0.0002124368,0.0002037997,0.0002316935,0.0002431879,0.0004659891,0.0005724524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002506296,"about_ca_system_score_gemma":0.0004064772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007044966,"about_ca_topic_score_gemma":0.001361676,"domain_scores_codex":[0.9998228,0.00002897883,0.00001695773,0.00003202893,0.000039567,0.00005971717],"domain_scores_gemma":[0.9999126,0.0000135132,0.00002645941,0.00001207696,0.00001739023,0.00001789833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008385409,0.0000546181,0.00007096009,0.0002016589,0.00001316532,0.0003176879,0.00007488691,0.0004451578,0.9895941,0.0006788613,0.0001806222,0.008284452],"study_design_scores_gemma":[0.00003550941,0.000766471,0.0006769891,0.000009846099,0.00001690863,0.0004724764,0.00002226545,0.0005115241,0.9917672,0.00008847278,0.005612731,0.00001970607],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9123945,0.008990628,0.06585787,0.000385298,0.0001654463,0.0006280942,0.0008905833,0.0006498144,0.01003782],"genre_scores_gemma":[0.9677362,0.003831352,0.02313524,0.00009171616,0.00002733589,0.0002050591,0.0004998934,0.00003654537,0.004436614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00187741,"threshold_uncertainty_score":0.006280541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01521935179073645,"score_gpt":0.2678955962389002,"score_spread":0.2526762444481638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}