{"id":"W1911225422","doi":"10.1111/ajt.13259","title":"Development and Impact of De Novo Anti-HLA Antibodies in Pediatric Heart Transplant Recipients","year":2015,"lang":"en","type":"article","venue":"American Journal of Transplantation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Hospital for Sick Children; University of Toronto","funders":"Hospital for Sick Children","keywords":"Medicine; Antibody; Cohort; Heart transplantation; Donor specific antibodies; Incidence (geometry); Human leukocyte antigen; Panel reactive antibody; Transplantation; Immunology; Isoantibodies; Internal medicine; Gastroenterology; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007062366,0.0002315581,0.0003566562,0.0007463973,0.0003095315,0.0005314689,0.0002425691,0.0003290316,0.0007220846],"category_scores_gemma":[0.00232662,0.0002176475,0.0002649541,0.0005949824,0.0003309693,0.0005992334,0.0003516596,0.0006541783,0.0001634508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002874893,"about_ca_system_score_gemma":0.0003382565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001102442,"about_ca_topic_score_gemma":0.0009262569,"domain_scores_codex":[0.9994975,0.0001079644,0.00006712541,0.00008528575,0.0001229835,0.0001192039],"domain_scores_gemma":[0.9972383,0.0006651774,0.001471596,0.0001081811,0.000162024,0.0003546471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00004618364,0.00002161333,0.9970124,0.000007435649,0.000008249854,0.0004743519,0.00004720722,0.00003272441,0.0002645951,0.00001364777,0.00002746759,0.002044195],"study_design_scores_gemma":[0.0000035266,0.0002907514,0.9941841,0.000008705974,0.00001710284,0.004798298,0.0001522957,0.0001106449,0.0002365917,0.00001629511,0.0001787452,0.000003082622],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992192,0.0004891611,0.00005481909,0.00001530193,0.00000220269,0.00000264134,0.00004030066,0.000001893293,0.0001745044],"genre_scores_gemma":[0.9991731,0.0005288155,0.0001019661,0.00002017141,0.00001256151,0.000004943744,0.0001081286,0.000001864386,0.00004849827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001102442,"threshold_uncertainty_score":0.003735006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03328225541216191,"score_gpt":0.3549727850590026,"score_spread":0.3216905296468408,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}