{"id":"W1912104500","doi":"10.1139/bcb-2014-0079","title":"<i>MicroRNA-139-5p</i> regulates C2C12 cell myogenesis through blocking Wnt/β-catenin signaling pathway","year":2014,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; National Institutes of Natural Sciences; National Natural Science Foundation of China","keywords":"C2C12; Myogenesis; Wnt signaling pathway; DKK1; Cell biology; Downregulation and upregulation; GSK-3; Catenin; Ectopic expression; Biology; Signal transduction; microRNA; Myocyte; Beta-catenin; Glycogen synthase; GSK3B; Cell growth; Chemistry; Cell culture; Biochemistry; Phosphorylation; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002595242,0.0003948224,0.0003037858,0.00003046988,0.0002116723,0.0000411223,0.0002989508,0.000620437,0.00005099903],"category_scores_gemma":[0.00005014063,0.0003892446,0.000163257,0.0001048078,0.0002645387,0.00000709857,0.00023193,0.0001173701,0.00001439729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002201018,"about_ca_system_score_gemma":0.00008159562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001618817,"about_ca_topic_score_gemma":0.000001750674,"domain_scores_codex":[0.9979814,0.0001288881,0.0003979921,0.0008892783,0.00009012967,0.0005123335],"domain_scores_gemma":[0.9989954,0.00004273418,0.0002480586,0.0004494947,0.0001019219,0.0001623951],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000789777,0.00007991763,0.0007610538,0.000143753,0.00003584797,0.000001925438,0.00003137216,0.00003712903,0.9968423,0.00003763951,0.0005176848,0.001432433],"study_design_scores_gemma":[0.0006888859,0.0001261187,0.00006226083,0.00002349401,0.00004950577,0.00002200579,0.00005412519,0.00004556357,0.9589126,0.0002436151,0.03929876,0.000473043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886844,0.006612625,0.0008008566,0.00008475265,0.0001472667,0.0001563615,0.00004864286,0.00004531574,0.003419754],"genre_scores_gemma":[0.9954779,0.0002599636,0.001279254,0.0002816575,0.0006012679,0.00002586887,0.0006663505,0.0000477713,0.001360037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03878108,"threshold_uncertainty_score":0.9998559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006936764321819939,"score_gpt":0.2067816016690845,"score_spread":0.1998448373472646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}