{"id":"W1912626499","doi":"10.1111/mmi.12274","title":"Molecular and structural basis of glutathione import in Gram‐positive bacteria via <scp>GshT</scp> and the cystine <scp>ABC</scp> importer <scp>TcyBC</scp> of <i><scp>S</scp>treptococcus mutans</i>","year":2013,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Rehabilitation Institute; University of Toronto","funders":"National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research; National Institutes of Health; Universiteit Gent; Fonds Wetenschappelijk Onderzoek","keywords":"Glutathione; Cystine; Biology; Biochemistry; Cysteine; Glutathione disulfide; Bacteria; ATP-binding cassette transporter; Glycine; Amino acid; Permease; Transporter; Enzyme; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006431837,0.0001632553,0.0000929665,0.00008715141,0.0002141343,0.0002135194,0.000181994,0.0003339151,0.0004114049],"category_scores_gemma":[0.0001130182,0.0001043452,0.0001994155,0.0001014202,0.0002639319,0.0002204337,0.0001594532,0.0003279577,0.0001872108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004199308,"about_ca_system_score_gemma":0.0002932786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001748778,"about_ca_topic_score_gemma":0.001336827,"domain_scores_codex":[0.999959,0.000006543256,0.000003830734,0.000007474678,0.00001550669,0.00000773488],"domain_scores_gemma":[0.9999356,0.000007723965,0.00002503493,0.000006613012,0.000007286895,0.00001772631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001066244,0.0000277018,0.0007039279,0.00003988584,0.000004392938,0.0002128746,0.00004672168,0.0005020709,0.9965725,0.0007261771,0.0000296636,0.001027411],"study_design_scores_gemma":[0.00002051131,0.0003362709,0.01678003,0.00000940154,0.00001901907,0.0007692298,0.0001591669,0.007679611,0.971401,0.0005187555,0.002292822,0.00001413695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983931,0.0002556488,0.0006651168,0.0001140727,0.000003349916,0.000005755434,0.00004693676,0.0000219903,0.000493898],"genre_scores_gemma":[0.9971197,0.0002973019,0.001810613,0.00002823502,0.000003170193,0.000007048617,0.0001955127,0.000006260202,0.0005321162],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001748778,"threshold_uncertainty_score":0.003477216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003413635723841114,"score_gpt":0.2028311821112379,"score_spread":0.1994175463873967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}