{"id":"W1913281097","doi":"10.1071/rdv17n2ab73","title":"73 ABNORMAL REPROGRAMMING OF HISTONE ACETYLATION IN CLONED BOVINE EMBRYOS","year":2004,"lang":"en","type":"article","venue":"Reproduction Fertility and Development","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Trichostatin A; Reprogramming; Somatic cell; Biology; Somatic cell nuclear transfer; Acetylation; Histone; Molecular biology; Histone H4; Cell biology; Anaphase; Embryo; Histone deacetylase; Embryogenesis; Genetics; Chromosome; Blastocyst; Cell; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002434635,0.0002679803,0.0003339546,0.0004795792,0.0001846824,0.0004204077,0.0002841894,0.0003070149,0.002078328],"category_scores_gemma":[0.0003260632,0.0002614789,0.0003863582,0.0002704701,0.0002080659,0.0001682461,0.0002513653,0.0004699062,0.0006676363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006212622,"about_ca_system_score_gemma":0.0002271358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003564905,"about_ca_topic_score_gemma":0.003019027,"domain_scores_codex":[0.9995111,0.00005443728,0.00005742506,0.0001363817,0.0001583751,0.0000822627],"domain_scores_gemma":[0.9997434,0.00006818501,0.00008089229,0.00002852122,0.00003437037,0.00004469547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004141457,0.000006919578,0.0003646302,0.00001770336,0.000003206923,0.0001196057,0.00001994973,0.00001631517,0.9986212,0.0000251748,0.00000978708,0.0007540381],"study_design_scores_gemma":[0.00001648178,0.0003494487,0.06982844,0.00002517127,0.00005900064,0.001686998,0.0001296221,0.0009298409,0.9213104,0.00006395706,0.005583311,0.00001733251],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860135,0.003460777,0.005307656,0.00007146373,0.000100961,0.00004182104,0.0009521113,0.0001191241,0.003932642],"genre_scores_gemma":[0.9887583,0.001484818,0.002298862,0.00006643566,0.00001475335,0.00003737979,0.001237397,0.00005974914,0.006042175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003564905,"threshold_uncertainty_score":0.007088304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01538937774375398,"score_gpt":0.2749951294315356,"score_spread":0.2596057516877817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}