{"id":"W1913281097","doi":"10.1071/rdv17n2ab73","title":"73 ABNORMAL REPROGRAMMING OF HISTONE ACETYLATION IN CLONED BOVINE EMBRYOS","year":2004,"lang":"en","type":"article","venue":"Reproduction Fertility and Development","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Trichostatin A; Reprogramming; Somatic cell; Biology; Somatic cell nuclear transfer; Acetylation; Histone; Molecular biology; Histone H4; Cell biology; Anaphase; Embryo; Histone deacetylase; Embryogenesis; Genetics; Chromosome; Blastocyst; Cell; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005692543,0.0001138469,0.0001377351,0.00006549499,0.00008181115,0.000008381904,0.00004667678,0.00009928099,0.000005352903],"category_scores_gemma":[0.0001318782,0.0001133877,0.00002799602,0.0001281675,0.00008356688,0.000008846744,0.00006888679,0.00007059406,0.000002325789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005015806,"about_ca_system_score_gemma":0.0001167106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000638763,"about_ca_topic_score_gemma":0.00004919649,"domain_scores_codex":[0.9986715,0.00002756841,0.0003848615,0.0006335715,0.0001297559,0.0001527851],"domain_scores_gemma":[0.9993593,0.000001590992,0.0001093436,0.0003471542,0.0001385145,0.00004406427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001287528,0.0004512566,0.02490685,0.00013827,0.00004360401,0.000001713447,0.0009034693,0.001144356,0.8949953,0.00007110155,0.00003045283,0.07602608],"study_design_scores_gemma":[0.0005157658,0.0001803431,0.4405906,0.00001630481,0.000004763488,0.0000140429,0.00013594,0.000005316251,0.5485874,0.00008877732,0.009730763,0.0001299836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954331,0.001464695,0.00228422,0.0002713691,0.0001774391,0.000233731,6.999331e-7,0.00001374192,0.0001209984],"genre_scores_gemma":[0.9927981,0.0001397311,0.006576645,0.00001830503,0.0000900279,0.00001798147,0.00004762865,0.000009154943,0.0003023657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4156838,"threshold_uncertainty_score":0.4623814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01538937774375398,"score_gpt":0.2749951294315356,"score_spread":0.2596057516877817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}