{"id":"W1913315326","doi":"10.1046/j.1365-2958.2003.03911.x","title":"Identification and characterization of NleA, a non‐LEE‐encoded type III translocated virulence factor of enterohaemorrhagic <i>Escherichia coli</i> O157:H7","year":2004,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":224,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; University of British Columbia; Michael Smith Health Research BC; Howard Hughes Medical Institute","keywords":"Biology; Effector; Pathogenicity island; Virulence; Type three secretion system; Enteropathogenic Escherichia coli; Citrobacter rodentium; Microbiology; Prophage; Escherichia coli; Genetics; Locus (genetics); Gene; Secretion; Intimin; Enterobacteriaceae; Bacteriophage; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001336652,0.0001969613,0.0003140504,0.00007607813,0.00004876032,0.000008966238,0.0002277792,0.0002068405,0.000008975536],"category_scores_gemma":[0.00005698042,0.0001953649,0.00007584502,0.0002440885,0.000334488,0.000007835045,0.0001189537,0.0001093088,0.00000352749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001820705,"about_ca_system_score_gemma":0.0001061785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004073681,"about_ca_topic_score_gemma":0.00001989567,"domain_scores_codex":[0.998745,0.0001112883,0.0004054763,0.0004067978,0.00007222869,0.0002591824],"domain_scores_gemma":[0.9991042,0.000008426569,0.0002226925,0.000319174,0.0002906439,0.00005486401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001973143,0.0001169393,0.0004464962,0.00009288958,0.000115326,0.000003482597,0.0001747696,0.00001615487,0.9985805,0.00002985662,0.000008795063,0.0002174925],"study_design_scores_gemma":[0.001006096,0.0004444918,0.00333423,0.00003014746,0.00003027051,0.0000114963,0.00003002934,0.00002930109,0.9945068,0.00001530203,0.0003994571,0.0001623281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883492,0.0005906682,0.01028347,0.0001177632,0.00009646389,0.0004162908,0.0001066812,0.0000101832,0.00002929894],"genre_scores_gemma":[0.998451,0.0004875678,0.0004172112,0.0001635899,0.00001809628,0.00002399504,0.0003474181,0.00002340802,0.00006773399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0101018,"threshold_uncertainty_score":0.7966748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007084774808025746,"score_gpt":0.236960652406131,"score_spread":0.2298758775981052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}