{"id":"W1913315326","doi":"10.1046/j.1365-2958.2003.03911.x","title":"Identification and characterization of NleA, a non‐LEE‐encoded type III translocated virulence factor of enterohaemorrhagic <i>Escherichia coli</i> O157:H7","year":2004,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":224,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; University of British Columbia; Michael Smith Health Research BC; Howard Hughes Medical Institute","keywords":"Biology; Effector; Pathogenicity island; Virulence; Type three secretion system; Enteropathogenic Escherichia coli; Citrobacter rodentium; Microbiology; Prophage; Escherichia coli; Genetics; Locus (genetics); Gene; Secretion; Intimin; Enterobacteriaceae; Bacteriophage; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001289203,0.0003955045,0.0004269681,0.0003918535,0.000130022,0.0004058226,0.0001488325,0.0003222785,0.0003429686],"category_scores_gemma":[0.0003510117,0.00009752726,0.0003746608,0.0002692457,0.0001806233,0.000250616,0.0002722691,0.0002523311,0.0003256025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001460849,"about_ca_system_score_gemma":0.0002171743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007649263,"about_ca_topic_score_gemma":0.0006402322,"domain_scores_codex":[0.9998915,0.00001051251,0.00001363598,0.00002696597,0.00003530326,0.00002211186],"domain_scores_gemma":[0.9997483,0.00004359811,0.00004746233,0.00001943905,0.00007321654,0.00006804821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005604399,0.00002918144,0.001583987,0.00005212926,0.000007828974,0.0002869607,0.00003588814,0.00002457146,0.9966714,0.00001796091,0.00002381872,0.001210111],"study_design_scores_gemma":[0.00003716397,0.0009494153,0.2301282,0.00005131211,0.0001203226,0.005852174,0.000877601,0.002669818,0.7508876,0.0001489046,0.00824325,0.00003428126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966293,0.000797873,0.001611055,0.0000448236,0.0000153343,0.00002914302,0.000533986,0.00001362659,0.0003248606],"genre_scores_gemma":[0.9817533,0.001364342,0.007476132,0.0001551995,0.00002929211,0.00004874666,0.006842078,0.00003477842,0.00229625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007649263,"threshold_uncertainty_score":0.001520932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007084774808025746,"score_gpt":0.236960652406131,"score_spread":0.2298758775981052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}