{"id":"W1913925477","doi":"10.1261/rna.046367.114","title":"The Ll.LtrB intron from <i>Lactococcus lactis</i> excises as circles in vivo: insights into the group II intron circularization pathway","year":2015,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Biology; Lactococcus lactis; Intron; Group II intron; Genetics; In vivo; Molecular biology; Gene; RNA splicing; RNA; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003765427,0.0002022744,0.0001651049,0.00003317427,0.0002984842,0.00009600988,0.00044295,0.0002174105,0.00002038498],"category_scores_gemma":[0.000275603,0.0001304666,0.00007878934,0.0001229051,0.00009442031,0.00001596011,0.0002012036,0.0001458971,0.00002834926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004982665,"about_ca_system_score_gemma":0.0001092405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006398177,"about_ca_topic_score_gemma":0.000918283,"domain_scores_codex":[0.9985443,0.0002964404,0.0002718463,0.000372111,0.0002521465,0.0002630954],"domain_scores_gemma":[0.9990459,0.00006171536,0.0001416546,0.0005856848,0.00006879622,0.00009625688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001363039,0.00005295593,0.0002232507,0.000003857991,0.00003514121,0.000004326496,0.0009079336,0.00001688652,0.967133,0.001748191,0.0005997038,0.02913841],"study_design_scores_gemma":[0.0004445512,0.0002463271,0.0004202482,0.00002381166,0.00001528919,0.000002613419,0.0005237813,0.00005723821,0.8362736,0.01537547,0.1464115,0.000205578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890258,0.003750373,0.003586888,0.0007819752,0.0004753594,0.0005604004,0.000006367316,0.00002432076,0.001788559],"genre_scores_gemma":[0.9979006,0.0005386732,0.0001393238,0.0004480177,0.0004861193,0.0001450178,0.00005992513,0.00003180762,0.0002504813],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1458118,"threshold_uncertainty_score":0.5320275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009218746145212,"score_gpt":0.2193927658435207,"score_spread":0.2101740196983087,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}