{"id":"W191409454","doi":"10.1007/978-1-62703-383-1_4","title":"Fluorescent Biosensors for the Detection of HMGB1 Release","year":2013,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institut National Du Cancer; Ligue Contre le Cancer; Institute of Cancer Research; Fondation pour la Recherche Médicale","keywords":"HMGB1; Programmed cell death; Extracellular; Cell biology; Immune system; Transfection; Cell; Green fluorescent protein; Biology; Apoptosis; Immunogenic cell death; Cancer cell; In vivo; Chemistry; Cell culture; Biochemistry; Cancer; Receptor; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008123326,0.0001000731,0.000140483,0.0001067962,0.00002600258,0.000004103988,0.0002129237,0.0001447532,0.000009973775],"category_scores_gemma":[0.001689006,0.00007587001,0.00006407327,0.0002180903,0.0001534572,0.000002167073,0.00008271237,0.0001165622,0.000001455009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001772692,"about_ca_system_score_gemma":0.00003357125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008532158,"about_ca_topic_score_gemma":0.00002346452,"domain_scores_codex":[0.9985553,0.0005715185,0.0002593306,0.0003186439,0.00004731738,0.0002479083],"domain_scores_gemma":[0.999206,0.0001529691,0.0000724894,0.000418067,0.0001211901,0.00002929823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005404982,0.00002770357,0.0003766337,0.0000132591,0.0000120179,3.486977e-7,0.0000135846,0.0003130619,0.8975886,0.000283582,0.000009837159,0.1013073],"study_design_scores_gemma":[0.0003823248,0.0001754261,0.001176711,0.000004013868,0.000003522985,0.000003007727,0.00004559618,0.0007840165,0.9864621,0.00235938,0.00851914,0.00008481681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.08065624,0.001850491,0.9160726,0.0004905094,0.0001246706,0.0007400031,0.000004454646,0.00000393569,0.00005708481],"genre_scores_gemma":[0.5498431,0.000375597,0.4490034,0.0001865258,0.00005779879,0.0003669093,0.00002412073,0.00002283441,0.0001197033],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.4691869,"threshold_uncertainty_score":0.3093889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02460084999098705,"score_gpt":0.4053235805229688,"score_spread":0.3807227305319817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}