{"id":"W1915115958","doi":"10.4049/jimmunol.177.2.1189","title":"Endogenous Tissue-Type Plasminogen Activator Is Protective during <i>Escherichia coli</i>-Induced Abdominal Sepsis in Mice","year":2006,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Plasmin; Peritoneal cavity; Plasminogen activator; Sepsis; Peritonitis; Escherichia coli; Endogeny; Immune system; Chemokine; Microbiology; Lipopolysaccharide; Molecular biology; Biology; Immunology; Chemistry; Medicine; Internal medicine; Endocrinology; Gene; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002940432,0.0006933074,0.000502358,0.0005126711,0.0002007753,0.0007064904,0.0003534101,0.0007256659,0.001117998],"category_scores_gemma":[0.0002552278,0.0003850413,0.0004043371,0.0002850936,0.0006792604,0.0005385158,0.0002940297,0.001559784,0.0006503853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003982332,"about_ca_system_score_gemma":0.0002760658,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002657049,"about_ca_topic_score_gemma":0.0002751007,"domain_scores_codex":[0.9996578,0.00007448538,0.00004550366,0.00007480437,0.00005278109,0.00009462275],"domain_scores_gemma":[0.9994062,0.00004956637,0.0002626331,0.00005625006,0.00003312625,0.0001923059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008961426,0.0001043476,0.0002159078,0.00004137877,0.000006646103,0.00008041007,0.00001710831,0.00006176758,0.9975581,0.0001112909,0.00003948119,0.0008673511],"study_design_scores_gemma":[0.0002114349,0.002061796,0.006151641,0.00003164477,0.0000368553,0.0007664362,0.00005179099,0.000955167,0.9877423,0.0001681865,0.001809555,0.00001308329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940801,0.001246299,0.002295804,0.0002648873,0.00004666411,0.00004118553,0.0007258238,0.0002487646,0.001050397],"genre_scores_gemma":[0.9932285,0.0009795396,0.002695243,0.0001468435,0.00002481063,0.00007821929,0.0007304045,0.00009486032,0.002021651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001117998,"threshold_uncertainty_score":0.003740072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01183723134180142,"score_gpt":0.226189557392257,"score_spread":0.2143523260504556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}