{"id":"W1915353445","doi":"10.1002/bit.25222","title":"Fluorescence‐based soft sensor for at situ monitoring of chinese hamster ovary cell cultures","year":2014,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chinese hamster ovary cell; Fluorophore; Fluorescence; Fluorescence spectroscopy; Biological system; In situ; Chemistry; Biology; Analytical Chemistry (journal); Biochemistry; Chromatography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005679503,0.000152149,0.0001415338,0.0000613003,0.000086887,0.000007526808,0.00009773539,0.0003288668,0.000002815598],"category_scores_gemma":[0.00004894254,0.0001228351,0.00007991018,0.00005938324,0.00008029061,0.000003075004,0.00009260032,0.00006570129,9.123913e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006360035,"about_ca_system_score_gemma":0.000007589524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002254504,"about_ca_topic_score_gemma":0.000001269472,"domain_scores_codex":[0.9993639,0.00001013375,0.000139766,0.000254504,0.00004490224,0.0001867805],"domain_scores_gemma":[0.9996335,0.0000159962,0.00005460124,0.0002149634,0.00003241916,0.00004851305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006531584,0.00002851945,0.01198831,0.0001133821,0.00002031026,4.760291e-7,0.000007875567,0.0004777165,0.9861835,0.00001432867,0.0001668652,0.000933461],"study_design_scores_gemma":[0.0004752087,0.0003009055,0.001483134,0.00002463839,0.00001372544,0.000005506546,0.00001158095,0.001341573,0.9907371,0.00002372615,0.005423805,0.0001590867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813819,0.001102831,0.01691221,0.0001025275,0.0002580895,0.0001354443,0.00001825926,0.00005418471,0.00003453881],"genre_scores_gemma":[0.9935515,0.00009469669,0.00598774,0.00003160846,0.0001823457,0.00002455511,0.00002340922,0.00001656728,0.00008760644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01216956,"threshold_uncertainty_score":0.5009068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005998811136702691,"score_gpt":0.2367974988319373,"score_spread":0.2307986876952346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}