{"id":"W1915353445","doi":"10.1002/bit.25222","title":"Fluorescence‐based soft sensor for at situ monitoring of chinese hamster ovary cell cultures","year":2014,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chinese hamster ovary cell; Fluorophore; Fluorescence; Fluorescence spectroscopy; Biological system; In situ; Chemistry; Biology; Analytical Chemistry (journal); Biochemistry; Chromatography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003462442,0.0003965385,0.0004017358,0.0002032224,0.0001322515,0.0002388908,0.0004404799,0.000455592,0.0005068627],"category_scores_gemma":[0.0003353936,0.0001608574,0.0002990436,0.0002431425,0.0001576264,0.0003199281,0.0002717649,0.0005757745,0.0002706794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000455852,"about_ca_system_score_gemma":0.0003146011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001048127,"about_ca_topic_score_gemma":0.001610997,"domain_scores_codex":[0.9997818,0.00003413551,0.00001365075,0.00006662826,0.00008853216,0.00001517021],"domain_scores_gemma":[0.9998431,0.00005784705,0.00003246597,0.00001521796,0.00004012753,0.00001118492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002383534,0.00001218989,0.0002089431,0.00005483856,0.000005168507,0.00001651226,0.00001569966,0.001110229,0.9938728,0.0001348033,0.00007510827,0.00446992],"study_design_scores_gemma":[0.0000054224,0.0001208045,0.0011448,0.000005004084,0.00001262522,0.00004208807,0.00001321209,0.04329155,0.9540787,0.00008755266,0.001182516,0.00001570101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6510854,0.001847391,0.3422327,0.0002077076,0.0001057548,0.0001189341,0.001196191,0.00115575,0.002050234],"genre_scores_gemma":[0.8456087,0.001165845,0.1485733,0.0001404314,0.00001937648,0.000270392,0.0006192893,0.00004348637,0.00355924],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001048127,"threshold_uncertainty_score":0.003307462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005998811136702691,"score_gpt":0.2367974988319373,"score_spread":0.2307986876952346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}