{"id":"W1916299283","doi":"10.1002/14651858.cd008167.pub3","title":"Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension","year":2012,"lang":"en","type":"review","venue":"Cochrane Database of Systematic Reviews","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor; Western University; University of British Columbia","funders":"","keywords":"Medicine; Blood pressure; Thiazide; Triamterene; Epithelial sodium channel; Internal medicine; Placebo; Amiloride; Randomized controlled trial; Spironolactone; Hydrochlorothiazide; Essential hypertension; Adverse effect; Pharmacology; Cardiology; Aldosterone; Sodium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002316116,0.0006195169,0.003728982,0.00009274032,0.0000995454,0.00001732888,0.0007133345,0.0003878603,0.000007905274],"category_scores_gemma":[0.0004033055,0.0003625354,0.00125018,0.0001501246,0.0001175412,0.00001292001,0.0001662286,0.0001833789,0.000007080725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001052881,"about_ca_system_score_gemma":0.0001060114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004082697,"about_ca_topic_score_gemma":0.000001971667,"domain_scores_codex":[0.996066,0.0003762032,0.002271472,0.0005102773,0.0004134133,0.0003626699],"domain_scores_gemma":[0.9951106,0.0002677337,0.002522024,0.001761319,0.0002396767,0.00009864597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00002964368,0.0001647228,7.858192e-7,0.9915071,0.0005583427,0.000001385324,0.00004481042,0.000003594571,0.003461828,0.00001120616,0.0001846111,0.004031943],"study_design_scores_gemma":[0.0009675905,0.0001782746,0.000004716284,0.7259029,0.02924572,0.0002014328,0.00003077813,0.00002249016,0.008618091,0.000001811137,0.2341333,0.0006929862],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001178828,0.990251,0.001127624,0.000008292639,0.0006184751,0.007153239,0.0006879468,0.000009026982,0.00002649002],"genre_scores_gemma":[0.002560721,0.9918656,0.000234599,0.00001465989,0.0006377248,0.0006989863,0.003749173,0.0000863969,0.0001521518],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.2656043,"threshold_uncertainty_score":0.9998826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0721407504366089,"score_gpt":0.3051378516111128,"score_spread":0.232997101174504,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}