{"id":"W1916558504","doi":"10.1039/c5mt00078e","title":"Arsenic(+3) and DNA methyltransferases, and arsenic speciation in tadpole and frog life stages of western clawed frogs (<i>Silurana tropicalis</i>) exposed to arsenate","year":2015,"lang":"en","type":"article","venue":"Metallomics","topic":"Arsenic contamination and mitigation","field":"Environmental Science","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Royal Military College of Canada","funders":"Basic Energy Sciences; Office of Science; Canadian Water Network; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Arsenobetaine; Arsenic; Arsenate; Methyltransferase; Chemistry; Excretion; Arsenic toxicity; Genetic algorithm; Biochemistry; Biology; Methylation; DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006355418,0.00029492,0.0001847352,0.000274853,0.0001981039,0.0002155127,0.0001654502,0.000281894,0.001672807],"category_scores_gemma":[0.00009106036,0.0002126914,0.0002375787,0.0001514336,0.0001651076,0.000233836,0.0001677022,0.0003390252,0.0002160248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002650207,"about_ca_system_score_gemma":0.0001297698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003378518,"about_ca_topic_score_gemma":0.006627195,"domain_scores_codex":[0.9999448,0.000006583824,0.000005252087,0.00002340994,0.00001022098,0.000009753674],"domain_scores_gemma":[0.9999117,0.000008206646,0.00003186535,0.000004683919,0.00001780145,0.00002585659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001688073,0.00001167087,0.002473302,0.00002846822,0.000009789321,0.00003820427,0.0000508987,0.00003450372,0.9963146,0.00001732056,0.00001959658,0.0008329148],"study_design_scores_gemma":[0.00002029078,0.001959646,0.3456115,0.00001973857,0.0001048875,0.0006310578,0.00049095,0.0005709468,0.6470488,0.00009139087,0.003426439,0.00002438916],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998471,0.000381324,0.0002187618,0.00002350597,0.000003659063,0.000006870197,0.0003459358,0.00001267864,0.0005363694],"genre_scores_gemma":[0.993879,0.0004382465,0.0007606567,0.00005038192,0.000003960907,0.00002648129,0.0008934235,0.00001061608,0.003937312],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003378518,"threshold_uncertainty_score":0.006717682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02140004740376717,"score_gpt":0.2324818463630071,"score_spread":0.21108179895924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}